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| '''[[Cytauxzoon|''Cytauxzoon felis'']] | | '''[[Cytauxzoon|''Cytauxzoon felis'']] |
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| + | '''[[Theileria|''Theileria'']] |
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− | ==''Theileria''==
| + | '''[[Piroplasmida Flashcards]] |
− | [[Image:Theileria parva life cycle.jpg|thumb|right|150px|''Theileria parva'' Life Cycle Diagram - Dennis Jacobs & Mark Fox RVC]]
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− | [[Image:Lymph node smear East Coast Fever.jpg|thumb|right|150px|Lymph node smear of a cow with East Coast Fever - Drs. Elizabeth Howerth and Bruce LeRoy, Department of Pathology, UGA College of Veterinary Medicine]]
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− | [[Image:H and E stain brain East Coast Fever.jpg|thumb|right|150px|H and E stain of brain and meningal vessels of a cow with East Coast Fever - Drs. Elizabeth Howerth and Bruce LeRoy, Department of Pathology, UGA College of Veterinary Medicine]]
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− | [[Image:Theileria cervi.jpg|thumb|right|150px|''Theileria cervi'' (deer) - Drs. Elizabeth Howerth and Bruce LeRoy, Department of Pathology, UGA College of Veterinary Medicine]]
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− | *Main species of veterinary importance is ''Theileria parva''
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− | **Causes '''East Coast Fever'''
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− | ***Severe, proliferative lymphatic disease of cattle
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− | ***Central and Eastern Africa
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− | ***Transmitted by [[Hard Ticks - Overseas|''Rhipicephalus appendiculatus'']]
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− | ***[[Ticks#Disease Transmission|Trans-stadial]] transmission
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− | *Other ''Theileria'' species cause production losses in cattle and sheep in the Middle East, Mediterranean and in Northern Africa
| + | </big> |
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− | '''Life Cycle'''
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− | *Incubation phase lasts 1 week
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− | *Lymphoblast proliferation
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− | **Local [[Lymph Nodes - Anatomy & Physiology|lymph node]] first infected then spreads through body
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− | **Occurs in week two
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− | *Lymphoid depletion
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− | **[[Lymphocytes - WikiBlood|Lymphocytes]] killed
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− | **Decreases lymphopoiesis
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− | **Occurs in week 3
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− | *Total incubation period takes about 18 days
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− | '''Diagnosis'''
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− | *Clinical signs
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− | **Pyrexia
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− | **Enlarged local [[Lymph Nodes - Anatomy & Physiology|lymph node]]
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− | ***Usually parotid [[Lymph Nodes - Anatomy & Physiology|lymph node]] as [[Hard Ticks - Overseas|''Rhipicephalus appendiculatus'']] feeds in the ear
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− | **Loss of condition
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− | *Examine Giemsa stained smears of:
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− | **Local [[Lymph Nodes - Anatomy & Physiology|lymph node]] aspirated for schizonts
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− | **Blood smears for piroplasms in red blood cells
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− | *Post-mortem
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− | **Pulmonary oedema
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− | **Gut mucosal haemorrhages
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− | **[[Lymph Nodes - Anatomy & Physiology|Lymph node]] and [[Spleen - Anatomy & Physiology|splenic]] cellular atrophy
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− | '''Control'''
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− | *Integrated control of both the [[Tick Control|tick vector]] and disease
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− | **[[Vaccines - WikiBlood|Vaccination]] and [[Ectoparasiticides]]
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− | | |
− | *Current [[Vaccines - WikiBlood|vaccination]] is live unattentuated
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− | **Contains frozen stabilate of ground up tick gut containing infective sporozoites
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− | **Long lasting oxytetracycline administered at the same time to slow down schizogony giving the immune response time to develop
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− | ==[[Protozoa Flashcards - Wikibugs#Piroplasmida|Piroplasmida Flashcards]]==
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