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− | {{unfinished}}
| + | #REDIRECT[[:Category:Yeast-like Fungi]] |
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− | {{toplink
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− | |backcolour =
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− | |linkpage =Fungi
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− | |linktext =FUNGI
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− | |pagetype=Bugs
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− | <br>
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− | [[Candidosis]]
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− | ==Cryptococcosis==
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− | *Over 19 species
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− | **''C. neoformans'' only major pathogen
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− | *Worldwide
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− | *Occurs in high concentrations in pigeon droppings (high creatinine concentration)
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− | **The pigeon is not infected
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− | **''C. neoformis'' colonise the droppings after they have been excreted
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− | **Also found in fruit, milk and soil
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− | *Exogenous, inhaled infection which is generally sporadic (non-contageous)
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− | **Can also be absorbed via skin penetration and ingestion
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− | *May be a primary pathogen or opportunistic
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− | *Targets the [[Cardiorespiratory System - Anatomy & Physiology|respiratory system]]
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− | **Including the [[Paranasal sinuses - Anatomy & Physiology|paranasal sinuses]]
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− | **Also can be systemic, cutaneous, visceral, skeletal or ocular
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− | *Causes sporadic mastitis in cattle
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− | **Can spread within the herd
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− | *Affects the [[Nervous and Special Senses - Anatomy & Physiology#Central Nervous System (CNS)|CNS]] of dogs and cats
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− | **[[Paranasal sinuses - Anatomy & Physiology|paranasal sinuses]] and [[Pharynx - Anatomy & Physiology|pharynx]] can be infected with dissemination to the [[Nervous and Special Senses - Anatomy & Physiology#Central Nervous System (CNS)|CNS]] and other tissues
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− | ***E.g. [[Lungs - Anatomy & Physiology|Lungs]], [[Urinary System - Anatomy & Physiology#The Kidney|kidneys]] and [[Joints - Anatomy & Physiology|joints]]
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− | **Also causes subcutaneous granulomas
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− | **The tip of the nose is a common site of infection in cats
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− | ***See [[Respiratory Fungal Infections - Pathology#In Cats|here]]
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− | *Causes myxoma-like lesions of the [[Lungs - Anatomy & Physiology|lung]] and [[Lips - Anatomy & Physiology|lip]] in horses
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− | *Causes cryptococcal meningitis in humans
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− | *Also affects dolphins, foxes, ferrets, monkeys, birds, cheetahs and guinea-pigs
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− | *Large yeast with capsule seen using India ink stain
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− | *Stains with PAS (Periodic acis Schiff)
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− | *Gram positive
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− | *Grows on blood agar and Sabouraud's Dextrose agar forming white, granular colonies which become slimy, mucoid and turn creamy/brown within a week
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− | *Species identified by carbohydrate assimilation tests
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− | *Antigen and antibody should be tested for as [[Immunoglobulins - WikiBlood|antibody]] formed by the body is soon overwhelmed and neutralised by abundent polysaccharide antigen from the capsule in active, systemic infections
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− | **Latex agglutination for [[Adaptive Immune System - WikiBlood#Actions of the Adaptive Immune System|antigen]], complement fixation, ELISA and IFAT can be used
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− | ==Geotrichosis==
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− | *''G. candidum''
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− | *Rare
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− | *Two forms: the yeast-like (glaborous) and fluffy
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− | *Affects a wide range of species
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− | *Usually diagnosed post-mortem
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− | *Affects the mucous membranes, udder, [[Bronchi and bronchioles - Anatomy & Physiology|bronchi]] and [[Lungs - Anatomy & Physiology|lungs]]
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− | *Usually mild, causing suppurative granulomas
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− | *Can be recovered from otitis externa infections in dogs
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− | *Organisms appear as rectangular or spherical arthrospores on wet mounts
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− | **Thick walled, non-budding, gram positive
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− | *Grow on Sabouraud's Dextrose agar
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− | **Membranous colonies
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− | **Do not grow well on blood agar
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− | ==''Malassezia pachydermidis''==
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− | [[Image:Malassezia pachydermidis.jpg|thumb|right|150px|''Malassezia pachydermidis'' - Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
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− | *Normally present in oily areas on the external [[Ear - Anatomy & Physiology|ear]] canal and [[Skin - Anatomy & Physiology|skin]] in dogs
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− | **Some strains have been recovered from the [[Ear - Anatomy & Physiology|ear]] canal of cats
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− | *Bottle-shaped, small budding cells, non-mycelial
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− | *Gram stain shows purple yeast cells with a very wide base
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− | *Grows on Sabouraud's Dextrose agar in 2 weeks of incubation at room temperature
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− | *Greenish discolouration on blood agar
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− | *Clinical disease may cause yeast to proliferate and cause infection
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− | *Grossly:
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− | **Regional lesions: muzzle, [[Ear - Anatomy & Physiology|ears]], interdigital, perianal
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− | **Or generalised disease
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− | **Erythematous, hyperpigmented, [[Skin Glossary - Pathology|lichenified]] and scaly lesions with alopecia
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− | *Microscopically:
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− | **[[Skin Glossary - Pathology|hyperkeratosis, parakeratosis]]
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− | **Spongiotic pustular dermatitis
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− | **[[Skin Glossary - Pathology|Acanthosis]]
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− | **Organisms are usually present- minimum 3-5 yeasts per high-power field must be found to imply cause of disease
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− | *''Malassezia pachydermis'' in [[Mycotic skin infections - Pathology#Malassezia dermatitis|malassezia dermatitis]]
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− | ==''Rhodotorula''==
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− | *''Rhodotorula minuta'' and ''R. rubra''
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− | *Canine [[Ear - Anatomy & Physiology|ear]] infections
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− | *Equine [[Female Reproductive Tract -The Uterus - Anatomy & Physiology|uterus]]
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− | *Seldom seen in animal infections
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− | ==''Torulopsis glabrata''==
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− | *Commensal in animals and is found in the soil
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− | *Implicated in cases of:
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− | **Pyelonephritis, pneumonia, septicaemia and meningitis (humans)
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− | **Mastitis and abortion in cattle
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− | **Systemic infection of monkeys and dogs
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− | ==Trichosporonosis==
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− | *Found in soil
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− | *Deuteromycetes yeast
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− | *''Trichosporonosis beigelii''
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− | **Implicated in feline nasal granuloma, [[Mycotic skin infections - Pathology#Superficial mycoses|skin infections]] in horses and monkeys, mastitis in cattle and sheep and in feline bladder infections
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− | *''T. capitum'' implicated in bovine mastitis
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− | ==Further Links==
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− | *[[Mycotic skin infections - Pathology]]
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− | *[[Antifungal Drugs]]
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