| Line 1: |
Line 1: |
| − | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big>
| + | #REDIRECT[[:Category:Brucella species]] |
| − | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big>
| |
| − | | |
| − | | |
| − | *''B. abortus'' occasionally in [[Joints - inflammatory#In Cattle|arthritis of cattle]]
| |
| − | | |
| − | | |
| − | *Isolated from closed cases of [[Bursae and Tendons - inflammatory#Poll Evil and Fistulous Withers|Poll Evil and Fistulous Withers]]
| |
| − | | |
| − | ===Overview===
| |
| − | | |
| − | *Important zoonoses worldwide
| |
| − | *Cause chronic granulomatous diseases
| |
| − | | |
| − | | |
| − | ===Characteristics===
| |
| − | | |
| − | *Small, non-moltile, Gram negative coccobacilli
| |
| − | *Facultatice intracellular pathogens
| |
| − | | |
| − | *6 species
| |
| − | | |
| − | ===Pathogenesis and pathogenicity===
| |
| − | | |
| − | *Penetrate nasal, oral or pharyngeal mucosa
| |
| − | *Phagocytosed and carried to regional lymph nodes
| |
| − | *Survive and multiply in cells of the reticulo-endothelial system
| |
| − | *Inhibit lysosome-phagosome fusion
| |
| − | *Lymph nodes enlarge (lymphatic and lymphoreticular hyperplasia) and inflammation is induced
| |
| − | *Surviving organisms spread to other organs (liver, spleen, placenta) and cause granulomatous reactions
| |
| − | *Eythritol is a growth stimulant and attracts the bacteria to the bovine placenta
| |
| − | *Infection of foetus and abortion
| |
| − | | |
| − | | |
| − | ===Clinical disease===
| |
| − | | |
| − | | |
| − | | |
| − | | |
| − | ===Diagnosis===
| |
| − | | |
| − | | |
| − | | |
| − | | |
| − | ===Control===
| |
| − | | |
| − | *Serological testing of milk (Milk Ring Test) and beef cattle (Rose Bengal Plate Test)
| |
| − | *Serological tests detect anti-lipopolysaccharide antibodies
| |