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− | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big>
| + | #REDIRECT[[:Category:Corynebacterium species]] |
− | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big>
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− | *''C. pyogenes'' in [[Joints - inflammatory#In Sheep|arthritis]] of sheep post-dipping joint infection and [[Joints - inflammatory#In Pigs|arthritis in pigs]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]]
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− | *''Corynebacterium pseudotuberculosis'' may cause [[Muscles - inflammatory#Abscesses|myositis]]
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− | *''Corynebacterium pseudotuberculosis'' in [[Bacterial skin infections#Deep pyoderma|deep pyoderma]]
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− | ===Overview===
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− | *Common inhabitants of skin and mucous membranes of animals
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− | *Opportunistic infections
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− | *Cause pyogenic infections
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− | *Most species host specific
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− | ===Characteristics===
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− | *Small, tough, Gram positive rods
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− | *Pleomorphic
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− | *Cluster together to resemble Chinese characters - coryneform morphology
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− | *Known as diphtheroids
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− | *Catalase positive, oxidase negative
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− | *Facultative anaerobes
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− | *Require enriched media for growth
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− | *Non-motile
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− | ===Pathogenesis and pathogenicity===
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− | *Pyogenic causing
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− | ===Clinical infections===
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− | *Infection follows tissue trauma
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− | *Suppurative lesions
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− | *''C. pseudotuberculosis'' casues caseous lymphadenitis in sheep
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− | *Carried on skin of sheep
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− | *Produces a phospholipase toxin
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− | *Infection through shearing wounds
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− | *Facultative intracellular pathogen inside macrophages
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− | *Ulcerative lymphangitis in horses
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− | ===Diagnosis===
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− | *Colony characteristics:
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− | **''C. bovis'': lipophilic bacterium; small, white, dry, non-haemolytic colonies on plates inoculated with bovine milk
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− | **''C. kutscheri'': white colonies; occasionally haemolytic
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− | **''C. pseudotuberculosis'': small, white coloniess surrounded by narrow zone of complete haemolysis; colonies become dry and cream-coloured
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− | **''C. renale'': small, non-haemolytic colonies after 24 hours; pigment produced after 48 hours
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− | *Biochemical reactions:
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− | **Certain strains of ''C. pseudotuberculosis'' reduce nitrates
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− | **All pathogenic strains except ''C. bovis'' produce urease
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− | *Enhancement of haemolysis produced by ''C. pseudotuberculosis'' when inoculated across a streak of ''Rhodococcus equi''
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