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<big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big>
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#REDIRECT[[:Category:Staphylococcus species]]
<big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big>
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*Gram positive cocci
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* [[General Pathology - Oedema#Permeability type|Permeability types of pulmonary oedema]].
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* Can cause haemorrhagic disease by [[General Pathology - Haemostasis#Secondary Thrombocytopenic Disease|secondary thrombocytopenic disease]].
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*May infect [[Joints - inflammatory#In Sheep|joints of sheep]] or become complication of '''tick-borne fever''', also [[Joints - inflammatory#In Pigs|arthritis in pigs]]
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==Staphylococcus hyicus==
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*Pigs - greasy pig disease
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*Exudative epidermitis due to ''Staphylococcus hyicus'' is a worldwide problem in piglets. 
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*The organism can often be isolated from the mucosa and skin of healthy adult pigs, and can persist in the environment for long periods. 
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*Disease occurs only in young piglets up to about 35 days of age. 
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*Passive transfer of antibodies from immune sows and development of immunity with age appear to adequately protect against disease. 
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*Piglets from non-immune sows are predisposed. 
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*Skin trauma, such as due to fighting, allowing entry of infective organisms is also considered a risk factor in this disease.
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===Pathology===
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[[Image:f00348.jpg]]
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===Pathogenesis===
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*''Staphylococcus hyicus'' produces an exfoliative toxin of approximately 30 kDa that causes separation of cells in the upper stratum spinosum resulting in rapid intraepidermal spread of organisms. 
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*Death of affected piglets is common and is attributed to dehydration, septicemia, or both. 
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*This porcine disorder has been likened to “scalded skin syndrome” in human neonates, due to skin infection by exfoliative toxin-producing ''Staphylococcus aureus''.
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===Differential diagnosis===
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*mange (Sarcoptes scabiei var. suis)
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*swine parakeratosis (zinc and essential fatty acid deficiency)
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*porcine juvenile pustular psoriasiform dermatitis (collarettes or rings typically on the ventrum of young pigs)
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*dermatosis vegetans (associated with a giant cell pneumonia)
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*dermatophytosis (most commonly Microsporum nanum)
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==Staphylococcus aureus==
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* May cause [[Intestines - disease due to pathogens#Staphylococcus|gastroenteritis]] in small animals.
 
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