Difference between revisions of "Bovine Parainfluenza - 3"
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**Stress caused by transport or mixing of stock | **Stress caused by transport or mixing of stock | ||
[[Category:Paramyxovirinae]] | [[Category:Paramyxovirinae]] | ||
| + | [[Category:Cattle]] | ||
Revision as of 11:31, 22 May 2010
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This article is still under construction. |
PI3
Pathogenesis
- Virulence varies with isolates
- Cessation of ciliary clearance and epithelial necrosis predisposes to secondary bacterial infections -> cough
- May cause rhinitis of cattle
Diagnosis
- Diseased lung tissue from dead animals or centrifuged cells from lung lavage
- Virus is too fragile for cell culture isolation (often inactivated in transport)
- Antigen detection by immunocytochemistry for intracytoplasmic viral inclusions containing labelled viral protein
- Serology: 4-fold rise in ELISA antibody in paired serum samples from several animals
Control
- Improve managemental factors
- All-in, all-out systems
- Some vaccination
- Temperature sensitive mutant that replicates at 34oC but not at 37oC
- Re-infection is common
Secondary Concerns
- With other agents causes calf pneumonia
- Associated with poor management:
- Overcrowding
- Poor ventilation
- High humidity
- Deprivation of colostrum
- Stress caused by transport or mixing of stock