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| − | <big><center>[[Pancreas Developmental - Pathology|'''BACK TO PANCREAS - DEVELOPMENTAL''']]</center></big>
| + | #REDIRECT[[Exocrine Pancreatic Insufficiency]] |
| − | <big><center>[[Pancreas - degenerative|'''BACK TO PANCREAS - DEGENERATIVE''']]</center></big>
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| − | <big><center>[[Pancreas Inflammatory - Pathology|'''BACK TO PANCREAS - INFLAMMATORY''']]</center></big>
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| − | <big><center>[[Pancreas - hyperplastic and neoplastic|'''BACK TO PANCREAS - HYPERPLASTIC AND NEOPLASTIC''']]</center></big>
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| − | *'''Exocrine pancreatic insufficiency (EPI)''' is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas
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| − | *Leading to insufficient activity of digestive enzymes in the lumen of the small intestine
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| − | *Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI
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| − | *Most common in dog - usually associated with [[Pancreas - degenerative|pancreatic atrophy]] or [[Pancreas Inflammatory - Pathology#Chronic Pancreatitis|chronic pancreatitis]]
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| − | *Occurs occasionally in other species, esp. calves with [[Pancreas Developmental - Pathology#Pancreatic hypoplasia|pancreatic hypoplasia]] and in cats
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| − | *'''Clinical signs'''
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| − | **Steatorrhoea
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| − | **Diarrhoea
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| − | **Weight loss
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| − | **Increased appetite
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| − | *In contrast, '''horses''' with very little pancreatic tissue develop '''hypoinsulinism''' but rarely EPI
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