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Line 15: |
| | ===[[Carcinoma]]s=== | | ===[[Carcinoma]]s=== |
| | | | |
| − | ===Gastrinoma=== | + | ===[[Gastrinoma]]=== |
| − | [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7762 Image of pancreatic garstrinoma in a dog from Cornell Veterinary Medicine] | |
| − | *Described in dogs, cats
| |
| − | *Known as Zollinger-Ellison syndrome in humans
| |
| − | *Uncommon compared to beta cell neoplasms
| |
| − | *Excess gastrin causes hyperacidity in the stomach and mucosal hyperplasia of the antral region causing gastric and [[Duodenum - Anatomy & Physiology|duodenal]] ulceration
| |
| − | ====Clinical signs====
| |
| − | *Anorexia
| |
| − | *Severe weight loss
| |
| − | *[[Control of Feeding - Anatomy & Physiology#The Vomit Reflex|Vomiting]]
| |
| − | *[[Diarrhoea]]
| |
| − | *Dehydration
| |
| − | ====Pathology==== | |
| − | *Multiple variably sized neoplasms
| |
| − | *Increased connective tissue mass - firm
| |
| − | *Partiallty encapsulated
| |
| − | *Invade locally
| |
| − | *Metastases to [[Liver - Anatomy & Physiology|liver]] and local lymph nodes are common
| |
| | | | |
| | ===Glucagonoma=== | | ===Glucagonoma=== |