Difference between revisions of "Mareks Disease"
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*'''Vaccines''' administered in ovo at 18 days | *'''Vaccines''' administered in ovo at 18 days | ||
[[Category:Herpesviridae]][[Category:Poultry]] | [[Category:Herpesviridae]][[Category:Poultry]] | ||
| + | [[Category:To_Do_-_Viruses]] | ||
Revision as of 22:41, 26 June 2010
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This article is still under construction. |
Caused by a herpesvirus
Hosts
- The most important disease of unvaccinated backyard chicken flocks
Pathogenesis
- Replicates initially in the lungs and B cells
- Enters feather follicles: produces virus-laden dander that is shed into litter
- Reaches T cells, causing proliferation without virus protein production
- T cells localize in brain or nerves causing encephalitis
- End stage: massive visceral tumors
Epidemiology
- More virulent strains evolving: presents a challenge to vaccinal immunity
Control
- Removal of litter between batches of chicks
- Vaccines administered in ovo at 18 days