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− | ===Parainfluenza- 3=== | + | ===[[Bovine Parainfluenza - 3]]=== |
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− | *Causative agent: [[Paramyxoviridae#Bovine Parainfluenza - 3 (PI-3)|parainfluenza- 3 virus]] (PI3)
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− | *On its own causes [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]]
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− | *Often part of multi-aetiology disease complex (e.g. [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]), often followed by [[:Category:Pasteurella and Mannheimia species|''Pasteurella sp.'']] obscuring viral origin
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− | *Replicates in airway epithelial cells and results in an initial [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchitis -> bronchiolitis]] -> extension into [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|alveoli]], causing [[Lungs Inflammatory - Pathology#Bronchointerstitial pneumonia|bronchointerstitial pneumonia]]
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− | *Early stages may show [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intracytoplasmic inclusions]]
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− | *The resulting exudate is predominantly neutrophilic
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− | *Positive confirmation lies in a Fluorescent Antibody Test (FAT) to the specific virus on frozen sections of tissue
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