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Created page with '===Inclusion body rhinitis=== [[Image:Inclusion body rhinitis.jpg|right|thumb|100px|<small><center>Inclusion body rhinitis (Image sourced from Bristol Biomed Image Archive with p…'
===Inclusion body rhinitis===
[[Image:Inclusion body rhinitis.jpg|right|thumb|100px|<small><center>Inclusion body rhinitis (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*[[Herpesviridae|'''Herpesviridae, porcine cytomegalovirus''']]
*Disease of suckling piglets 1-5 wks of age
*Clinical signs: those associated with acute/subacute [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]] (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old)
*May progress to [[Paranasal Sinuses Inflammatory - Pathology#Sinusitis|sinusitis]], otitis media or [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]]
*Morbitity high, mortality low
*Gross pathology - catarrhal discharge becoming purulent (secondary infection)
*Histology:
**Large basophilic [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intranuclear inclusion bodies]] in the surface and subepithelium of nasal and sinus glandular epithelium with lymphocytic infiltration of the mucosa
**Bursting of nucleus with cell necrosis and sloughing of necrotic epithelium
*Can develop viraemic stage, with inclusions and focal necrotising lesions in other organs eg: renal tubular epithelium
**Usually younger piglets, can die during this phase
*Usually resolves if uncomplicated but rhinitis may persist if secondary infection is present
*May persist in pulmonary macrophages
[[Category:Herpesviridae]][[Category:Pig]][[Category:To_Do_-_Viruses]]
[[Image:Inclusion body rhinitis.jpg|right|thumb|100px|<small><center>Inclusion body rhinitis (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*[[Herpesviridae|'''Herpesviridae, porcine cytomegalovirus''']]
*Disease of suckling piglets 1-5 wks of age
*Clinical signs: those associated with acute/subacute [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]] (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old)
*May progress to [[Paranasal Sinuses Inflammatory - Pathology#Sinusitis|sinusitis]], otitis media or [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]]
*Morbitity high, mortality low
*Gross pathology - catarrhal discharge becoming purulent (secondary infection)
*Histology:
**Large basophilic [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intranuclear inclusion bodies]] in the surface and subepithelium of nasal and sinus glandular epithelium with lymphocytic infiltration of the mucosa
**Bursting of nucleus with cell necrosis and sloughing of necrotic epithelium
*Can develop viraemic stage, with inclusions and focal necrotising lesions in other organs eg: renal tubular epithelium
**Usually younger piglets, can die during this phase
*Usually resolves if uncomplicated but rhinitis may persist if secondary infection is present
*May persist in pulmonary macrophages
[[Category:Herpesviridae]][[Category:Pig]][[Category:To_Do_-_Viruses]]