Changes

**'''[[Thrombosis|Thrombosis of the portal vein]]''', '''hepatic arteriovenous fistulae''' and '''congenital hypoplasia of the portal vein.'''

**'''[[Thrombosis|Thrombosis of the portal vein]]''', '''hepatic arteriovenous fistulae''' and '''congenital hypoplasia of the portal vein.'''

The pathophysiology of PSS relates to the shunting of portal blood directly from the systemic circulation, resulting in hyperammonaemia and [[Hepatic Encephalopathy|hepatic encephalopathy]].  Animals with PSS also have reduced function of the hepatic component of the monocyte phagocyte system (chiefly the Kupffer cells) and they often develop bacteraemia.  Gram negative bacteria deriving from the GI tract are involved most commonly.

The pathophysiology of PSS relates to the shunting of portal blood directly into the systemic circulation, resulting in hyperammonaemia and [[Hepatic Encephalopathy|hepatic encephalopathy]].  Animals with PSS also have reduced function of the hepatic component of the monocyte phagocyte system (chiefly the Kupffer cells) and they often develop bacteraemia.  Gram negative bacteria deriving from the GI tract are involved most commonly.

==Signalment==

==Signalment==