Difference between revisions of "Mandibular Osteomyelitis"

Revision as of 20:03, 26 July 2010

Description

bovine actinomycosis, 3-years-old bull, 2-month evolution. (L. Mahin 2008, Wikimedia commons)

Lumpy jaw is a chronic infectious condition which affects cattle. It is caused by the anaerobic filamentous bacteria Actinomyces bovis Actinomyces is a normal commensal of the oral cavity and upper respiratory tract of cattle, it gains entery to underlying soft tissue when the mucosa is damaged by trauma or eruption of teeth.

Signalment

The condition affects cattle 2-5 yrs old, those that are exposed to sharp objects whilst feeding and when the teeth are erupting. It is found worldwide but is most prevelent in Western and mid-western states of the USA.

Diagnosis

The condition is easily diagnosed on clinical signs and can be confirmed by crushing and staining the yellow granules expressed with the pus from skin leisions to reveal gram-positive filamentous rods.

Clinical signs

Facial distortment
Granuloma formation overlying the mandible and maxila
Fistulae draining small amounts of thick pus
Difficulties with mastication
Loose teeth
Dyspnoea

Pathology=

3 major features:

Inflammatory removal of bone. As cortex of bone is pushed out by central inflammation produces thinning of bone cortex with proliferation of new periosteal bone. The centre of the mandible is eroded forming a honeycomb-like bone. Eventually will erode through bone producing granulomatous lesion on bottom of mandible and eventually eroding through skin.
Granuloma with micro abscess's in centre with greenish / yellow granules in middle of pus. These granules known as "sulphur bodies". Sulphur body is a colony of tangled mass of Actinomyces filaments. This is surrounded by neutrophils and macrophages forming a pyogenic granuloma.
Masses of fibrous tissue surround the granuloma and fill the spaces where bone has been destroyed

Treatment

Treatment is difficult due to the nature of the leisions and poor antibiotic penetration.

Prognosis

Treatment is rarely successful and recurrence of leisions is common; slaughter is advised.

References

Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) Bovine Medicine (Second edition), Blackwell Publishing
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial

Also known as:

Lumpy jaw

@@ Line 27: / Line 27: @@
 *Dyspnoea
-===Pathology===
+===Pathology====
+major features:
+#Inflammatory removal of bone. As cortex of bone is pushed out by central inflammation produces thinning of bone cortex with proliferation of new periosteal bone. The centre of the [[Skull and Facial Muscles - Anatomy & Physiology#Mandible (mandibula)|mandible]] is eroded forming a honeycomb-like bone. Eventually will erode through bone producing [[Granuloma|granulomatous]] lesion on bottom of [[Skull and Facial Muscles - Anatomy & Physiology#Mandible (mandibula)|mandible]] and eventually eroding through skin.
+#Granuloma with micro abscess's in centre with greenish / yellow granules in middle of pus. These granules known as "sulphur bodies". Sulphur body is a colony of tangled mass of Actinomyces filaments. This is surrounded by [[Neutrophils|neutrophils]] and [[Macrophages|macrophages]] forming a pyogenic granuloma.
+#Masses of fibrous tissue surround the granuloma and fill the spaces where bone has been destroyed
 ==Treatment==
@@ Line 38: / Line 43: @@
 * Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) '''Bovine Medicine''' (Second edition), ''Blackwell Publishing''
 * Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''
-====Pathology====
-major features:
-#Inflammatory removal of bone. As cortex of bone is pushed out by central inflammation produces thinning of bone cortex with proliferation of new periosteal bone. The centre of the [[Skull and Facial Muscles - Anatomy & Physiology#Mandible (mandibula)|mandible]] is eroded forming a honeycomb-like bone. Eventually will erode through bone producing [[Granuloma|granulomatous]] lesion on bottom of [[Skull and Facial Muscles - Anatomy & Physiology#Mandible (mandibula)|mandible]] and eventually eroding through skin.
-#Granuloma with micro abscess's in centre with greenish / yellow granules in middle of pus. These granules known as "sulphur bodies". Sulphur body is a colony of tangled mass of Actinomyces filaments. This is surrounded by [[Neutrophils|neutrophils]] and [[Macrophages|macrophages]] forming a pyogenic granuloma.
-#Masses of fibrous tissue surround the granuloma and fill the spaces where bone has been destroyed.
 [[Category:Teeth_-_Inflammatory_Pathology]]
 [[Category:Cattle]]
 [[Category:To_Do_- lizzyk]]