Changes

===Diagnosis===

===Diagnosis===

Diagnosis is confirmed in most affected animals (other than pigs) by demonstration of large numbers of rod-shaped ''B. anthracis'' in the blood and most other tissues. A tissue sample from a fresh carcass may be collected from an incision made in a well vascularised area such as the ear. In pigs, a small piece of lymphatic tissue should be collected aseptically and submitted. Diagnostic tests include bacterial culture, PCR and fluorescent antibody stains for demonstration of the bacillus in blood or tissue.

Diagnosis is confirmed in most affected animals (other than pigs) by demonstration of large numbers of rod-shaped ''B. anthracis'' in the blood or tissue. A tissue sample from a fresh carcass may be collected from an incision made in a well vascularised area such as the ear. As pigs with localised disease are rarely bacteraemic, a small piece of lymphatic tissue should be collected aseptically and submitted. Diagnostic tests include bacterial culture, PCR and fluorescent antibody stains for demonstration of the bacillus in blood or tissue.

===Pathology===

===Pathology===

Bloody discharges from body orifices may be observed in carcasses and ''Rigor mortis'' is often absent or incomplete in dead animals. Failure of the blood to clot and splenomegaly are other important ''post mortem'' findings. Lymph nodes are often swollen and oedematous. Haemorrhages may be found on the serosal surfaces of the thorax and abdomen as well as the endocardium.

Bloody discharges from body orifices may be observed in carcasses and ''rigor mortis'' is often absent or incomplete in dead animals. Failure of the blood to clot and splenomegaly are other important ''post mortem'' findings. Lymph nodes are often swollen and oedematous. Haemorrhages may be found on the serosal surfaces of the thorax and abdomen as well as the endocardium.

===Treatment===

===Treatment===