Difference between revisions of "Sendai Virus"

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**Kill whole colony in an outbreak -> disinfection -> formalin fumigation
 
**Kill whole colony in an outbreak -> disinfection -> formalin fumigation
 
[[Category:Paramyxovirinae]][[Category:Rodents]]
 
[[Category:Paramyxovirinae]][[Category:Rodents]]
[[Category:To_Do_-_Viruses]]
+
[[Category:To_Do_-_Clinical/Viruses]]

Revision as of 12:25, 30 July 2010

Murine Parainfluenza - 1 (Sendai Virus)

  • Endemic in many mouse colonies
  • Most mice show no symptoms due to maternal antibodies
  • But minor respiratory lesions may invalidate carcinogenic or toxicological studies
  • Immunological studies also confused due to virus activating NK cells via high circulating IF 3-4 days post-infection
  • Control achieved by:
    • Purchasing specific pathogen free (SPF) mice
    • Kill whole colony in an outbreak -> disinfection -> formalin fumigation