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==Diagnosis==
==Diagnosis==
The history and clinical signs are important in order to differentiate whether the condition is primary or secondary. In the case of primary photosensitisation there is often a history of exposure to plants containing photodynamic agents such as St. John's Wort or clover. Alternatively, there may be a history of administration of drugs such as phenothiazines, sulphonamides or tetracyclines.
The history and clinical signs are important in order to differentiate whether the condition is primary or secondary. In the case of primary photosensitisation there is often a history of exposure to plants containing photodynamic agents such as St. John's Wort or clover. Alternatively, there may be a history of administration of drugs such as phenothiazines, sulphonamides or tetracyclines. Signs of liver disease are usually absent.
In animals affected by secondary photosensitisation, the classic skin lesions are accompanied by signs of liver disease. Serum biochemistry often reveals increased liver enzymes (ALP, GGT, SDH and ALT).