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Redirected page to Category:Spleen - Pathology
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#REDIRECT[[:Category:Spleen - Pathology]]
 
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|backcolour = f5fffa
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|linkpage =Lymphoreticular & Haematopoietic System - Pathology
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|linktext =Lymphoreticular & Haematopoietic System
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|maplink = Lymphoreticular & Haematopoietic System (Content Map) - Pathology
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|sublink1 =Secondary Lymphoid System - Pathology
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|subtext1 =SECONDARY LYMPHOID SYSTEM
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|pagetype =Pathology
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''NB:Be aware of age-related changes regarding the spleen''
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==Splenic Lesions==
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*splenomegaly is the main clinical finding associated with the spleen in disease
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===Splenitis===
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===Anthrax===
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===Torsion===
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===Haemolytic Anaemia===
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===Chronic Venous Congestion===
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*this may be seen along with chronic venous congestion of the liver in cases of chronic cardiac failure
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===Barbituates===
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* administration of barbituates can produce a degree of splenomegaly due to splenic engorgement by erythrocytes
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===Splenic Tumours===
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*these are important surgically since splenomegaly can be diagnoses clinically by palpation or X-ray and some are surgically curable
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====Hyperplastic Nodules or Benign Lymphoma====
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*very common incidental findings in older dogs
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*should not be mistakenly identified as pathognomic lesions
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*consist of nodules of hyperplastic white and red pulp
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:- usually 1-2 cms in size, but occasionally may be larger
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:- spherical
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:- protrude hemispherically from the surface as yellow and red mottled nodules
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*infrequently, may rupture and give rise to haemorrhage
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====Haemangioma====
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*benign tumour of dogs
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*may grow to considerable size
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:- the size of the lesion giving rise to clinical signs is compounded by haemorrhage from and into the tumour
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:- thus, a large mass of apple size may be found protruding from the spleen and adherent to the omentum
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*on section, it is largely blood clot
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*responds well to surgery
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:- therefore it must be distinguished from haemangiosarcoma
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====Haemangiosarcoma====
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*highly malignant tumour of dogs
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*distinguished from the superficially similar haemangioma by the presence of much more formed, solid tumour tissue
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*accurate prognosis demands histological examination
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*secondaries are common locally in the [[Peritoneal cavity - Anatomy & Physiology#Omentum|omentum]] and in the [[Liver - Anatomy & Physiology|liver]]
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:- course is usually short, often only a month or two
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:- metastases may occur in almost every organ
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====Haematopoietic Neoplasms====
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=====lymphosarcoma=====
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* splenomegaly occurs in multicentric lymphosarcoma
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*splenic enlargement may be marked if any form of lymphosarcoma is in leukaemic phase
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=====myeloid (granulocytic) leukaemia=====
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*rare
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*all species
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*extreme form with spleen approaching liver size
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=====systemic mastocytosis=====
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*cat
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*extreme form with spleen approaching liver size
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===Infarction===
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===Rupture===
 
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