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=~~==Deficiencies of~~ Innate Immunity===

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|pagetitle =Primary Innate Immunity Deficiencies

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=~~===[[Canine Cyclic Haematopoiesis]]====~~

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<categorytree mode=pages>Primary Innate Immunity Deficiencies</categorytree>

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~~====Canine Leukocyte Adhesion Deficiency (CLAD)====~~

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*Occurs in Irish Setters

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*Missence mutation of -Cys-36-Ser- in CD18 molecule

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**CD18 is required for [[Neutrophils|neutrophil]] migration and phagocytosis

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*Recurrent bacterial infection

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*Neutrophilia ([[Neutrophils|neutrophils]] remain in the blood and are unable to fight infection in the tissue)

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~~[[Category:Primary Innate Immunity Deficiencies]]~~

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~~====Bovine Leukocyte Adhesion Deficiency (BLAD)====~~

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[[Category:Primary Immunodeficiency|A]]

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*Occurs in Holstein cattle

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*Missence mutation of -Asp-128-Gly in CD18 molecule

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*Recurrent infection, e.g. pneumonia

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~~[[Category:Primary Innate Immunity Deficiencies]]~~

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[[Category:Primary Immunodeficiency]]

Bara

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Category:Primary Innate Immunity Deficiencies (view source)

Revision as of 14:23, 12 August 2010