Changes

Erythrophagocytosis may be evident and parasitised erythrocytes will become spherical.

Erythrophagocytosis may be evident and parasitised erythrocytes will become spherical.

The organism must be differentiated from Howell-Jolly bodies and other parasites. Due to the cyclic parasitaemia the organism causes, negative blood smears will not rule out the organism.

The organism must be differentiated from Howell-Jolly bodies and other parasites. Due to the cyclic parasitaemia the organism causes, negative blood smears will not rule out the disease.

Additionally Immunofluorescence of blood smears demonstrates the organism.

Additionally Immunofluorescence of blood smears can demonstrate the organism.

When the organism is not found a presumptive diagnosis may be made with clinical signs of reduced packed cell volume, and other causes of a regenerative anaemia ruled out.

Haematology will show a decreased packed cell volume and a regenerative anaemia.

===Clinical signs===

===Clinical signs===