Difference between revisions of "Case 1"
Jump to navigation
Jump to search
(15 intermediate revisions by one other user not shown) | |||
Line 19: | Line 19: | ||
The following data and pictures were taken at post-mortem examination: | The following data and pictures were taken at post-mortem examination: | ||
− | |||
'''Cardiovascular system''': | '''Cardiovascular system''': | ||
− | |||
*Heart has a ''globoid'' shape | *Heart has a ''globoid'' shape | ||
*Ventricular wall measurements: | *Ventricular wall measurements: | ||
− | **Interventricular septum; 12mm | + | **Interventricular septum; 12mm |
**Right ventricular wall; 3mm | **Right ventricular wall; 3mm | ||
**Left ventricular wall; 10mm | **Left ventricular wall; 10mm | ||
*Pericardium is fatty, shiny and intact | *Pericardium is fatty, shiny and intact | ||
− | + | [[Image:hypertrophic cardiomyopathy 2.jpg|right|thumb|125px|<small><center>'''Hypertrophic cardiomyopathy (cat)'''. Courtesy of T. Scase</center></small>]] | |
No embolic thrombi were found in the abdominal aorta. | No embolic thrombi were found in the abdominal aorta. | ||
− | |||
No further abnormalities were found. | No further abnormalities were found. | ||
− | |||
==Histopathology== | ==Histopathology== | ||
− | [[Image:Case pic 3.jpg| | + | [[Image:Case pic 3.jpg|left|thumb|125px|<small><center>'''Histology; hypertrophic cardiomyopathy'''. Courtesy of K. Hughes</center></small>]] |
Samples were taken for histological examination (Stained with H and E): | Samples were taken for histological examination (Stained with H and E): | ||
*The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts). | *The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts). | ||
− | |||
Some sections were stained with Massons Trichrome: | Some sections were stained with Massons Trichrome: | ||
− | * This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface. | + | *This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface. |
− | * Multifocally the fibrosis surrounds individual atrophied myocytes. | + | *Multifocally the fibrosis surrounds individual atrophied myocytes. |
− | * There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries. | + | *There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries. |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− |
Revision as of 12:02, 31 August 2007
Signalment
- 7 year old
- Male neutered
- Domestic short haired cat
History
- Fully vaccinated
- Sudden death at home
- No other clinical abnormalities
Imaging
Haematology/Biochemistry
Gross Pathology
The following data and pictures were taken at post-mortem examination:
Cardiovascular system:
- Heart has a globoid shape
- Ventricular wall measurements:
- Interventricular septum; 12mm
- Right ventricular wall; 3mm
- Left ventricular wall; 10mm
- Pericardium is fatty, shiny and intact
No embolic thrombi were found in the abdominal aorta.
No further abnormalities were found.
Histopathology
Samples were taken for histological examination (Stained with H and E):
- The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts).
Some sections were stained with Massons Trichrome:
- This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface.
- Multifocally the fibrosis surrounds individual atrophied myocytes.
- There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries.