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<big><center>[[Alimentary - Anatomy & Physiology|'''BACK TO ALIMENTARY - ANATOMY & PHYSIOLOGY''']]</center></big>
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#REDIRECT[[:Category:Large Intestine - Anatomy & Physiology]]
 
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==Introduction==
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The large intestine extends from the [[Ileum - Anatomy & Physiology|ileum]] of the [[Small Intestine - Anatomy & Physiology|small intestine]] to the [[Anus - Anatomy & Physiology|anus]]. Water, electrolytes and nutrients are absorbed, concentrating the ingesta into faeces. Faeces are stored prior to defeacation. No chemical digestion takes place; there is no secretion of enzymes. All species have a large microbial population living in the large intestine, which is of particular importance to the [[Hindgut Fermenters - Anatomy & Physiology|hindgut fermenters]]. For this reason, hindgut fermenters have a more complex large intestine with highly specialised regions for fermentation.
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The large intestine can be divided into:
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*[[Caecum - Anatomy & Physiology|Caecum]]
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*[[Colon - Anatomy & Physiology|Colon]]
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*[[Rectum - Anatomy & Physiology|Rectum]]
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*[[Anus - Anatomy & Physiology|Anus]]
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==Structure==
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==Function==
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==Vasculature==
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*The '''cranial mesenteric artery''' supplies the caecum, ascending and part of the transverse colon.
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*The '''caudal mersenteric artery''' supplies the rest of the transverse colon, the descending colon and the rectum.
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==Innervation==
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*Like the [[Small Intestine - Anatomy & Physiology|small intestine]], the large intestine recieves sympathetic and parasympathetic innervation.
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*Neurones interact with the myenteric plexus to affect contractility, and with the submucosal plexus to affect secretions.
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**The '''sympathetic '''have coeliac, cranial mesenteric and caudal mesenteric ganglia.
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**As the sympathetic fibres leave the ganglia, they surround their respective artery.
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**'''Parasympathetic''' innervation stimulates peristalsis.
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==Lymphatics==
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[[Image:Colon fox lymphatic nodule.jpg|thumb|right|150px|Lymphatic Nodule - Copywright RVC 2008]]
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*Lymphatic nodules are present in the mucosa.
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==Histology==
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[[Image:mucosal layer of colon.jpg|thumb|right|150px|Mucosal Layer of Colon (Fox) - Copywright RVC 2008]]
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*The mucosa of the large intestine is smooth; there are '''no villi'''.
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*Mucosal glands are much longer and straighter.
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*The number of goblet cells in the mucosa is increased compared to the small intestine.
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**Mucus is very important for lubrication of the ingesta as it passes through the intestine, particularly as more water is absorbed from the lumen making it drier.
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*There are numerous scattered lymph nodules.
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**The number of lymph nodules increases compared to the small intestine.
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*The submucosa is much reduced in thickness.
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*'''Taenia''' may be present.
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**These are concentrations of the longitudinal muscle layer into long bands.
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**When the taenia contract, they cause shortening of the large intestine, which produces saccualtions, or '''haustra'''.
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*Many glands are present in the mucosa and skin of the anal region.
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==Species Differences==
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===Carnivore===
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*The dog and cat posses two [[Anus - Anatomy & Physiology#Species Differnces|anal sacs]].
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===Ruminant===
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===[[Hindgut Fermenters - Horse - Anatomy & Physiology|Horse]]===
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===Pig===
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*Taenia present
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==Links==
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[[The Small and Large Intestines|Pathology of the Small and Large Intestine]]
 
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