Neonatal isoerythrolysis is a disease of humans and domestic animals and has been observed in newborn cats, horses, pigs, cows and rarely in dogs. It is characterised by immune-mediated haemolytic anaemia due to ingestion of maternal colostral antibody directed against surface antigens on neonatal red blood cells. This leads to extravascular and intravascular haemolysis during the first few days of life.
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Neonatal isoerythrolysis is a disease of humans and domestic animals and has been most commonly observed in newborn cats and horses. Rarely it has also been described in other species following blood transfusions, vaccination or previous pregnancy. The disease is characterised by immune-mediated haemolytic anaemia due to ingestion of maternal colostral antibody directed against surface antigens on neonatal red blood cells. This leads to extravascular and intravascular haemolysis during the first few days of life.
==Pathogenesis==
==Pathogenesis==
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*Mair, T. S. (1998) '''Equine Medicine, Surgery and Reproduction''' ''Elsevier Health Sciences''
*Mair, T. S. (1998) '''Equine Medicine, Surgery and Reproduction''' ''Elsevier Health Sciences''
*Norsworthy, G. D., Crystal, M., Grace, S. F. (2006) '''The Feline Patient''' ''Wiley-Blackwell''
*Norsworthy, G. D., Crystal, M., Grace, S. F. (2006) '''The Feline Patient''' ''Wiley-Blackwell''
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*Silvestre-Ferreira, A. C., Pastor, J. (2010) '''Feline Neonatal Isoerythrolysis and the Importance of Feline Blood Types''' ''Veterinary Medicine International Volume 2010''