*MHC I presents '''endogenous''' (that is, intracellular) peptides
+
MHC I presents '''endogenous''' (intracellular) peptides. Viral proteins are broken down to peptides by the proteasome and transferred to the endoplasmic reticulum (ER) via transporters associated with antigen processing (TAP) molecules. In the ER peptides are processed with empty MHC I molecules and exported to the cell surface for presentation to the T-cell receptors of [[Lymphocytes#Cytotoxic CD8+|'''CD8+ T-cells''']]
−
*Viral proteins are broken down to peptides by the proteasome and transferred to the endoplasmic reticulum via TAP (Transporters associated with Antigen Processing) molecules
−
*In the ER peptides are processed with empty MHC I molecules and exported to the cell surface for presentation
−
* MHC class I molecules present these to the T-cell receptors of [[Lymphocytes#Cytotoxic CD8+|'''CD8+ T-cells''']]