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Systemic Lupus Erythematosus (view source)
Revision as of 16:00, 8 October 2010
, 16:00, 8 October 2010no edit summary
==Description==
Also known as: '''''SLE and Multi-systemic immune mediated disease
==Introduction==
Systemic Lupus Erythematous is an immune-mediated disease which can affect many different organ systems. The immune system is directed against various tissues of the body and immune complexes cause a [[Type III Hypersensitivity|type III hypersensitivity reaction]]. The condition is documented in cats and dogs but the etiology is not known. The disease has been reported in colonies of dogs suggesting that there may be a genetic or infectious component to the cause.
Systemic Lupus Erythematous is an immune-mediated disease which can affect many different organ systems. The immune system is directed against various tissues of the body and immune complexes cause a [[Type III Hypersensitivity|type III hypersensitivity reaction]]. The condition is documented in cats and dogs but the etiology is not known. The disease has been reported in colonies of dogs suggesting that there may be a genetic or infectious component to the cause.
===Clinical Signs===
===Clinical Signs===
Clinical signs depend on the tissues and organ systems affected by the condition. A combination of the following signs may be seen:
Clinical signs depend on the tissues and organ systems affected by the condition. A combination of the following signs may be seen:
* Immune-mediated haemolytic anaemia
* Immune-mediated haemolytic anaemia
* Immune-mediated thrombocytopenia
* Immune-mediated thrombocytopenia