Changes

==Introduction==

==Introduction==

[[Image:SSC-like lesion donkey.jpg|right|thumb|200px|<small><center>Squamous cell carcinoma-like lesion. This resolved with potassium iodide therapy suggesting that it was in fact a pyogranuloma.(Image courtesy of  [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]

[[Image:SSC-like lesion donkey.jpg|right|thumb|200px|<small><center>Squamous cell carcinoma-like lesion. This resolved with potassium iodide therapy suggesting that it was in fact a pyogranuloma.(Image courtesy of  [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]

Treatment and prognosis depend on the tumour type, site and extent.

Treatment and prognosis depend on the tumour type, site and extent.

Treatment options are effectively limited to '''surgical excision''' or '''cryosurgery'''. There are no scientific comparative

Treatment options are effectively limited to '''surgical excision''' or '''cryosurgery'''. There are no scientific comparative studies on the use of cisplatin, 5-fluorouracil or radiation in donkeys and, given the paucity of literature reports, it is difficult to predict which treatments are best in any particular circumstances. Typically for all neoplastic diseases the best prognosis is likely to be achieved with aggressive treatment of small lesions.

studies on the use of cisplatin, 5-fluorouracil or radiation in donkeys and, given the paucity of literature reports, it is difficult to predict which treatments are best in any particular circumstances. Typically for all neoplastic diseases

the best prognosis is likely to be achieved with aggressive treatment of small lesions.

Prognosis should be considered before embarking on therapy. Orbital involvement carries a poor prognosis.

Prognosis should be considered before embarking on therapy. Orbital involvement carries a poor prognosis.

* Extensive tumours may require enucleation

* Extensive tumours may require enucleation.

* Surgical excision of the tumour carries a 55% recurrence rate in horses

* Surgical excision of the tumour carries a 55% recurrence rate in horses.

* Treatment may require referral and hospitalisation, as effective treatments may involve radiotherapy, cryotherapy or immunotherapy. Costs may be considerable. Specialist advice should be sought

* Treatment may require referral and hospitalisation, as effective treatments may involve radiotherapy, cryotherapy or immunotherapy. Costs may be considerable. Specialist advice should be sought.

==Prevention==

==Prevention==

It is difficult to give any advice regarding prevention, but sunlight is a potential carcinogen for nonpigmented

It is difficult to give any advice regarding prevention, but sunlight is a potential carcinogen for nonpigmented skin. Exposure to sun of the ear tips and non-pigmented eyelids or nictitans mucosa may be significant factors.

skin. Exposure to sun of the ear tips and non-pigmented eyelids or nictitans mucosa may be significant factors.

 

 

 

==References==

==References==