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==Introduction==
 
==Introduction==
 
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[[Image:Photosensitisation donkey.jpg|right|thumb|200px|<small><center>Photosensitisation (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
Donkeys are liable to the full range of toxic skin disease and perhaps the
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Donkeys are liable to the full range of toxic skin disease and perhaps the most alarming is '''photosensitization''' arising as a '''result of chronic/terminal liver failure'''. Most are due to '''hepatotoxic plants''' (and some dangerous chemical poisons with severe destructive hepatic effects). For example, '''ragwort (''Senecio jacobaea'')''' is highly toxic to donkeys.  
most alarming is '''photosensitization''' arising as a '''result of chronic/terminal liver failure'''. Most are due to '''hepatotoxic plants''' (and some dangerous chemical poisons with severe destructive hepatic effects). For example,
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'''ragwort (''Senecio jacobaea'')''' is highly toxic to donkeys.  
      
==Clinical Signs==
 
==Clinical Signs==
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'''Advanced liver failure '''signs may be present to guide the clinician, but sometimes '''photosensitization'''
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'''Advanced liver failure '''signs may be present to guide the clinician, but sometimes '''photosensitization''' is the first sign. '''Extensive, exudative, inflammatory dermatitis''' arises over exposed areas of the skin. Interestingly, in the donkey, it is D. Knottenbelt's experience that the eruptions are not necessarily always confined to the white skinned areas, although the white areas are invariably much worse.
is the first sign. '''Extensive, exudative, inflammatory dermatitis''' arises over
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exposed areas of the skin. Interestingly, in the donkey, it is my experience
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that the eruptions are not necessarily always confined to the white skinned
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areas, although the white areas are invariably much worse.
      
==Aetiology==
 
==Aetiology==
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No matter what the cause, clearly the first measures are to prevent
 
No matter what the cause, clearly the first measures are to prevent
 
further damage by '''removing the donkey from sunshine'''. Soothing '''antibiotic creams and lotions''' can help and many cases will improve significantly with this alone. '''Alterations in diet''' may be required and avoidance of primary photosensitizing plants is important. It sometimes takes several weeks before the risks of further exposure/actinic damage have cleared.
 
further damage by '''removing the donkey from sunshine'''. Soothing '''antibiotic creams and lotions''' can help and many cases will improve significantly with this alone. '''Alterations in diet''' may be required and avoidance of primary photosensitizing plants is important. It sometimes takes several weeks before the risks of further exposure/actinic damage have cleared.
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==Literature Search==
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[[File:CABI logo.jpg|left|90px]]
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Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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<br><br><br>
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[http://www.cabdirect.org/search.html?q=%28ab%3A%28photosensitisation%29+OR+ab%3A%28photosensitization%29+OR+ab%3A%28photosensitivity%29+OR+ab%3A%28photosenzitivity%29%29+AND+od%3A%28donkeys%29 Photosensitisation in donkeys related publications]
    
==References==
 
==References==
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|linkpage =Chemical and Toxic Skin Disorders - Donkey
 
|linkpage =Chemical and Toxic Skin Disorders - Donkey
 
|linktext =Chemical and Toxic Skin Disorders - Donkey
 
|linktext =Chemical and Toxic Skin Disorders - Donkey
|rspace={{Donkey}}
   
|pagetype=Donkey
 
|pagetype=Donkey
 
}}
 
}}
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{{infotable
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|Maintitle = [[Sponsors#The Donkey Sanctuary|This section was sponsored and content provided by '''THE DONKEY SANCTUARY''']]
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|Maintitlebackcolour = B4CDCD
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}}
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[[Category:Donkey]]
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[[Category:Chemical and Toxic Skin Disorders - Donkey]]
Author, Donkey, Bureaucrats, Administrators
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