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{{review}}
   
[[Image:Donkey Europe.JPG|thumb|right|200px|<small><center>Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary]</center></small>]]  
 
[[Image:Donkey Europe.JPG|thumb|right|200px|<small><center>Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary]</center></small>]]  
 
Current best practice aspects of sedation in donkeys are described in detail in [[Anaesthesia and Sedation - Donkey|Anaesthesia and Sedation]]. A brief outline of the pharmacology of some of the agents used commonly in donkeys for sedation and analgesia is given below. These agents should never be administered without appropriate preanaesthetic evaluation and preparation and adequate monitoring is essential (Matthews and Van Dijk, 2004).
 
Current best practice aspects of sedation in donkeys are described in detail in [[Anaesthesia and Sedation - Donkey|Anaesthesia and Sedation]]. A brief outline of the pharmacology of some of the agents used commonly in donkeys for sedation and analgesia is given below. These agents should never be administered without appropriate preanaesthetic evaluation and preparation and adequate monitoring is essential (Matthews and Van Dijk, 2004).
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These agents are '''highly protein-bound''' and should be used with care in hypoalbuminemia and concomitantly with other highly protein-bound drugs. Benzodiazepines should also be used with caution in animals with impaired hepatic function and concurrently with agents that also undergo hepatic metabolism, ''e.g.'' [[Macrolides and Lincosamides|erythromycin]], [[Gastroprotective Drugs#Histamine (H2) Receptor Antagonists|cimetidine]]. Zolazepam is only available in a fixed combination with the dissociative anaesthetic [[Anaesthetics - Donkey#Ketamine and Tiletamine|tiletamine]].
 
These agents are '''highly protein-bound''' and should be used with care in hypoalbuminemia and concomitantly with other highly protein-bound drugs. Benzodiazepines should also be used with caution in animals with impaired hepatic function and concurrently with agents that also undergo hepatic metabolism, ''e.g.'' [[Macrolides and Lincosamides|erythromycin]], [[Gastroprotective Drugs#Histamine (H2) Receptor Antagonists|cimetidine]]. Zolazepam is only available in a fixed combination with the dissociative anaesthetic [[Anaesthetics - Donkey#Ketamine and Tiletamine|tiletamine]].
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==Literature Search==
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[[File:CABI logo.jpg|left|90px]]
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Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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<br><br><br>
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[http://www.cabdirect.org/search.html?q=(title:(sedative)+OR+subject:(sedatives))+AND+(ab:(donkey)+OR+title:(donkey)) Sedatives in donkeys publications]
    
==References==
 
==References==
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[[Category:Donkey]]
 
[[Category:Donkey]]
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[[Category:Pharmacology_-_Donkey]]
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[[Category:Anaesthesia_and_Sedation_-_Donkey]]
Author, Donkey, Bureaucrats, Administrators
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