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− | {{review}}
| + | [[Image:Donkey lying down.JPG|thumb|right|200px|<small><center>Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary]</center></small>]] |
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| [[Opioids]] (''e.g.''''' butorphanol, buprenorphine''') are classified either as (full) agonists, agonist-antagonists (partial agonists) or antagonists based on differing affinities and efficacy at μ-, κ- and δ-opioid receptors, which results in activation of descending inhibitory pathways and reduction in the transmission of nociceptive signals to higher centres in the brain. Opioid | | [[Opioids]] (''e.g.''''' butorphanol, buprenorphine''') are classified either as (full) agonists, agonist-antagonists (partial agonists) or antagonists based on differing affinities and efficacy at μ-, κ- and δ-opioid receptors, which results in activation of descending inhibitory pathways and reduction in the transmission of nociceptive signals to higher centres in the brain. Opioid |
| receptors are widespread, resulting in a '''wide range of side effects''' including <u>respiratory depression, increased intracranial pressure, hypotension and inhibition of peristalsis,</u> which vary depending on the agent used. | | receptors are widespread, resulting in a '''wide range of side effects''' including <u>respiratory depression, increased intracranial pressure, hypotension and inhibition of peristalsis,</u> which vary depending on the agent used. |
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| '''The neuroleptanalgesic combination of the potent opioid etorphine with the phenothiazine ACP should NOT be used in donkeys.''' | | '''The neuroleptanalgesic combination of the potent opioid etorphine with the phenothiazine ACP should NOT be used in donkeys.''' |
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| + | ==Literature Search== |
| + | [[File:CABI logo.jpg|left|90px]] |
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| + | |
| + | Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation). |
| + | <br><br><br> |
| + | [http://www.cabdirect.org/search.html?q=(title:(opioid)+OR+subject:(opioids))+AND+(ab:(donkey)+OR+title:(donkey)+OR+od:(donkeys)) Opioids in donkeys publications] |
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| ==References== | | ==References== |
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| |linkpage =Pharmacology - Donkey | | |linkpage =Pharmacology - Donkey |
| |linktext =Pharmacology - Donkey | | |linktext =Pharmacology - Donkey |
− | |rspace={{Donkey}}
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| |pagetype=Donkey | | |pagetype=Donkey |
| }} | | }} |
| + | {{infotable |
| + | |Maintitle = [[Sponsors#The Donkey Sanctuary|This section was sponsored and content provided by '''THE DONKEY SANCTUARY''']] |
| + | |Maintitlebackcolour = B4CDCD |
| + | }} |
| + | [[Category:Donkey]] |
| + | [[Category:Pharmacology_-_Donkey]] |