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Current best practice aspects of anaesthesia in donkeys are described in detail in [[Anaesthesia and Sedation - Donkey|Anaesthesia and Sedation]]. A brief outline of the pharmacology of some of the agents used commonly in donkeys for anaesthesia and analgesia is given below. These agents should never be administered without appropriate preanaesthetic evaluation and preparation and adequate monitoring is essential (Matthews and Taylor, 2000; Matthews and Van Dijk, 2004).
 
Current best practice aspects of anaesthesia in donkeys are described in detail in [[Anaesthesia and Sedation - Donkey|Anaesthesia and Sedation]]. A brief outline of the pharmacology of some of the agents used commonly in donkeys for anaesthesia and analgesia is given below. These agents should never be administered without appropriate preanaesthetic evaluation and preparation and adequate monitoring is essential (Matthews and Taylor, 2000; Matthews and Van Dijk, 2004).
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Guaifenesin, a centrally acting skeletal muscle relaxant with only mild sedative and analgesic effects, can be administered intravenously to donkeys in combination with xylazine and ketamine for extended periods of general anaesthesia (Matthews and Taylor, 2000). Careful monitoring of the depth of anaesthesia is essential, particularly because donkeys are more sensitive
 
Guaifenesin, a centrally acting skeletal muscle relaxant with only mild sedative and analgesic effects, can be administered intravenously to donkeys in combination with xylazine and ketamine for extended periods of general anaesthesia (Matthews and Taylor, 2000). Careful monitoring of the depth of anaesthesia is essential, particularly because donkeys are more sensitive
 
(40% less required to produce recumbency) to guaifenesin than horses (Matthews et al, 1997; Matthews and Taylor, 2000). '''Overdosage''' is associated with abnormal respiration nystagmus, hypotension, and contradictory muscle rigidity.
 
(40% less required to produce recumbency) to guaifenesin than horses (Matthews et al, 1997; Matthews and Taylor, 2000). '''Overdosage''' is associated with abnormal respiration nystagmus, hypotension, and contradictory muscle rigidity.
      
==Suggested combination regimens for sedative/tranquillisers, opioids and anaesthetic agents in donkeys==
 
==Suggested combination regimens for sedative/tranquillisers, opioids and anaesthetic agents in donkeys==
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Due to the longer duration of action of bupivacaine, nerve blocks should not
 
Due to the longer duration of action of bupivacaine, nerve blocks should not
 
be repeated within four to six hours to avoid accumulation and toxicity.
 
be repeated within four to six hours to avoid accumulation and toxicity.
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==Literature Search==
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[[File:CABI logo.jpg|left|90px]]
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Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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<br><br><br>
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[http://www.cabdirect.org/search.html?q=(title:(anaesth*)+OR+subject:(anaesth*)+OR+title:(anesth*)+OR+subject:(anesth*))+AND+(ab:(donkey)+OR+title:(donkey)+OR+od:(donkeys)) Anaesthesia in donkeys publications]
    
==References==
 
==References==
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|linkpage =Pharmacology - Donkey
 
|linkpage =Pharmacology - Donkey
 
|linktext =Pharmacology - Donkey
 
|linktext =Pharmacology - Donkey
|rspace={{Donkey}}
   
|pagetype=Donkey
 
|pagetype=Donkey
 
}}
 
}}
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{{infotable
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|Maintitle = [[Sponsors#The Donkey Sanctuary|This page was sponsored and content provided by '''THE DONKEY SANCTUARY''']]
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|Maintitlebackcolour = B4CDCD
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}}
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[[Category:Donkey]]
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[[Category:Pharmacology_-_Donkey]][[Category:Anaesthesia_and_Sedation_-_Donkey]]
Author, Donkey, Bureaucrats, Administrators
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