Changes

==Non-regenerative Anaemia==

==Non-regenerative Anaemia==

The failure to regenerate indicates that there must be some failure to produce red blood cells in the bone marrow.  Erythrocytes are produced from stem cells in the bone marrow and they then undergo sequential stages of maturation before and after they are released into the circulation.   

The failure to regenerate indicates that there is a failure to produce red blood cells in the bone marrow.  Erythrocytes are produced from stem cells in the bone marrow and they then undergo sequential stages of maturation before and after they are released into the circulation.   

*Failure of the bone marrow stem cells to produce cells of the erythroid lineage

 

**'''[[Immune Mediated Haemolytic Anaemia|Pure red cell aplasia]]'''

===Failure of the bone marrow stem cells to produce erythroid cells===

**Aplastic anaemia

This occurs in the following conditions:

**Bone marrow suppression

*'''[[Immune Mediated Haemolytic Anaemia|Pure red cell aplasia]]'''

**Myelophthisis

*Aplastic anaemia

**Myelodysplasia

*Bone marrow suppression

*Failure of maturation

*Myelophthisis

**Iron deficiency

*Myelodysplasia

**Vitamin B12/folate deficiency

 

===Failure of erythrocyte maturation===

*Iron deficiency

*Vitamin B12/folate deficiency

[[Category:Anaemia|A]][[Category:Dog]][[Category:Cat]][[Category:Horse]][[Category:Cattle]][[Category:Donkey]][[Category:Sheep]][[Category:Pig]]

[[Category:Anaemia|A]][[Category:Dog]][[Category:Cat]][[Category:Horse]][[Category:Cattle]][[Category:Donkey]][[Category:Sheep]][[Category:Pig]]