Difference between revisions of "Permethrin Toxicity"
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Permethrin is the active ingredient of many 'spot-on' paraciticides used in the control of fleas and ticks in dogs <ref> '''Clinical effects and outcome of feline permethrin spot-on poisonings reported to the Veterinary Poisons information Service (VPIS), London''', ''Journal of Feline Medicine and Surgery''(2007)'''9''',335-339 accessed on http://www.fabcats.org/esfm/permethrin.pdf 07.11.2010 </ref>. | Permethrin is the active ingredient of many 'spot-on' paraciticides used in the control of fleas and ticks in dogs <ref> '''Clinical effects and outcome of feline permethrin spot-on poisonings reported to the Veterinary Poisons information Service (VPIS), London''', ''Journal of Feline Medicine and Surgery''(2007)'''9''',335-339 accessed on http://www.fabcats.org/esfm/permethrin.pdf 07.11.2010 </ref>. | ||
==Signalment== | ==Signalment== | ||
| − | Permethrin poisoning in most commonly seen in cats who have inadvertently been administered spot-on | + | Permethrin poisoning in most commonly seen in cats who have inadvertently been administered spot-on products intended for use in dogs, or who have had contact with dogs following application of the preparations <ref> '''BSAVA Manual of Canine and Feline Emergency and Critical Care''', Chapter 19, Second Edition, 2007 </ref>. |
==Diagnosis== | ==Diagnosis== | ||
===Clinical Signs=== | ===Clinical Signs=== | ||
Revision as of 20:39, 7 November 2010
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This article is still under construction. |
Introduction
Permethrin is the active ingredient of many 'spot-on' paraciticides used in the control of fleas and ticks in dogs [1].
Signalment
Permethrin poisoning in most commonly seen in cats who have inadvertently been administered spot-on products intended for use in dogs, or who have had contact with dogs following application of the preparations [2].
Diagnosis
Clinical Signs
Laboratory Tests
Pathology
The spot-on canine preparations are often quite concentrated. In dogs and other animals,on whom they are considered safe to use, permethrin is metabolised by the enzyme glucuronidase transferase to glucouronides and sulphates. The cat lack this ezyme thus leading to an increased half life of permethrin in this species.
Treatment
Prognosis
References
- ↑ Clinical effects and outcome of feline permethrin spot-on poisonings reported to the Veterinary Poisons information Service (VPIS), London, Journal of Feline Medicine and Surgery(2007)9,335-339 accessed on http://www.fabcats.org/esfm/permethrin.pdf 07.11.2010
- ↑ BSAVA Manual of Canine and Feline Emergency and Critical Care, Chapter 19, Second Edition, 2007