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| ::Biochemistry - Hypoalbuminaemia and hypoglycaemia. | | ::Biochemistry - Hypoalbuminaemia and hypoglycaemia. |
| '''Urinalysis''' : may have proteinuria, casts, pyuria. A uniary tract infection may be present with the same organism as is responsible for the endocarditis. | | '''Urinalysis''' : may have proteinuria, casts, pyuria. A uniary tract infection may be present with the same organism as is responsible for the endocarditis. |
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| '''Blood cultures''' : Requires 3-4 sterile samples colected from the jugular vein at least 1 hour apart over a 24 hour period. Negative cultures do not rule out the possibility of bacerial endocarditis. | | '''Blood cultures''' : Requires 3-4 sterile samples colected from the jugular vein at least 1 hour apart over a 24 hour period. Negative cultures do not rule out the possibility of bacerial endocarditis. |
| ===Echocardiography=== | | ===Echocardiography=== |
| + | Structural abnormalities and vegetations may be visible on the valves although it is difficult to differentate from [[endocardiosis]]. |
| ===Radiography=== | | ===Radiography=== |
| + | Radiography is often unremarkable. There may be evidence of cardiomegaly or congestive heart failure if valvular damage is chronic or severe. Evidence of a focus of infection such as discospondylitis may be visible. |
| ===Electrogcardiogram (ECG)=== | | ===Electrogcardiogram (ECG)=== |
| + | ECG may be normal. Arrhythmias detectected are often ventricular in origin (e.g. ventricular premature complexes) and represent extension fo the inflammatory focus to invlove the moycoardium. 3rd degree heart block may be present if the AV node is affected. |
| ==Treatment== | | ==Treatment== |
| + | Antibiotic treatment with either a broad spectrum antibiotic or an appropriate antibiotic based on cultre and sensitivity results. Antibiotics should be administered intravenously for the first 5 days of therapy followed by a proloned course (>4 weeks) of oral medication. |
| + | Common Protocols use Ampicillin in combination with fluoroqunilone such as enrofloxacin. |
| + | Secondary problems such as septic shock, D.I.C., congestive heart failure and embolisation need to be managed. |
| ==Prognosis== | | ==Prognosis== |
| + | Long term prognosis is guarded to poor. Possible complications include septic shock, Disseminated Intravascular coagulation, congestive heart failure and embolisation to other organs. |
| ==References== | | ==References== |
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− | =from clinical=
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− | =====Laboratory Findings=====
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− | -'''Urine analysis'''
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− | *If UTI is present, could be (+/-) for the same bacteria that caused endocarditis
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− | *Proteinuria
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− | *Casts
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− | *Pyuria
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− | *Hematuria
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− | -'''Blood Culture'''
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− | *collect blood from the jugular vein
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− | *3-4 sterile samples taken 1 hour apart over 24 hours and grown in enhancement media
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− | *Positive culture (Rare)
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− | *Negative culture is not diagnostic
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− | -'''Blood Profiles:'''
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− | *Hematology=leukocytosis, neutrophilia, monocytosis, nonregenerative anemia, thrombocytopenia (See with development of: disseminated intravascular coagulation); clotting times may be prolonged
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− | *Biochemistry=hypoalbumenemia, hypoglycemia (if septic), signs of complications from emboli
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− | =====Radiography=====
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− | -Usually normal unless severe damage is present
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− | -Left atrial and ventricular enlargement (Mitral Valve Incompetence)
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− | -Right atrial and ventricular enlargement (Aortic Valve Incompetence)
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− | -Signs of congestive heart failure with chronic/severe valve damage
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− | =====Electrocardiography (ECG)=====
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− | -Usually normal
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− | -Arrhythmias (especially ventricular premature complexes; AV node damage causes 3rd degree AV block)
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− | =====Echocardiography=====
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− | -Vegetative lesions on valves and/ mural surfaces
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− | ====Treatment====
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− | -Antibiotic given I/V for at least five days and then given orally for at least six weeks
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− | (Broad Spectrum or Culture/Sensitivity)
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− | -Manage secondary problems:
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− | (e.g. septic shock, congestive heart failure, embolization, D.I.C.)
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− | ====Prognosis====
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− | -Guarded
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− | (Possibility of recurrent infections, embolic complications, congestive heart failure)
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| [[Category:Endocardial_Pathology]][[Category:Cardiovascular_System_-_Inflammatory_Pathology]][[Category:Cattle]][[Category:Pig]][[Category:Sheep]] | | [[Category:Endocardial_Pathology]][[Category:Cardiovascular_System_-_Inflammatory_Pathology]][[Category:Cattle]][[Category:Pig]][[Category:Sheep]] |
| [[Category:To_Do_-_Cardiovascular]] | | [[Category:To_Do_-_Cardiovascular]] |