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* Renal involvement may become significant.
 
* Renal involvement may become significant.
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===Water Excess===
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* Known as "water intoxication".
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====Causes====
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* Results from induced hypo-osmolality, e.g.
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** Excessive administration of water to previously deprived animals.
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** Administration of large volumes of water to animals with acute renal failure.
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====Effects====
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* The ECF osmolality is reduced. 
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* Water is transferred to the cells and they become "water-logged". 
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** Intracellular oedema in the CNS results in convulsions and death.
      
[[Category:Vascular Fluid]]
 
[[Category:Vascular Fluid]]
 
[[Category:Cardiology Section]]
 
[[Category:Cardiology Section]]
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