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| − | ==Introduction==
| + | #REDIRECT[[:Category:Degenerations and Infiltrations]] |
| − | * Degenerations and infiltrations are the morphological manifestation of an altered metabolism within the cell.
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| − | ** A particular kind of change within a cell or tissue may suggest that a specific type of alteration has occurred.
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| − | * Degenerations and infiltrations are types of structural changes.
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| − | ** These are best considered at a cellular level.
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| − | ** These structural changes are deviations from the cell's normal structure and function.
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| − | *** Parameters are outside the normal physiological range for the cell.
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| − | * '''Degeneration'''
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| − | ** The tissue cell shows some change in itself.
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| − | * '''Infiltration'''
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| − | ** Something accumulates in the cell or tissue.
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| − | ==[[Cellular Swelling]]==
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| − | ==[[Hydropic Degeneration]]==
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| − | ==[[Cellular Fatty Change]]==
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| − | ==[[Mucoid Degeneration]]==
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| − | ==[[Hyaline Degeneration]]==
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| − | ==[[Glycogen Infiltration]]==
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| − | ==Cellular Inclusions==
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| − | ===[[Viruses|Viruses]]===
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| − | * Either in the nucleus or cytoplasm.
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| − | ===Storage Products===
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| − | * Due to '''hereditary storage diseases''' in which there is a missing or defective cellular enzyme. There are many types known in domestic animals.
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| − | ** Break down/ build up of intracellular substances is halted.
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| − | *** The intermediate substance accumulates in the lysosomes.
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| − | ** Affects all tissues
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| − | *** The central nervous system is particularly vulnerable.
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| − | * Due to '''age'''
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| − | ** Lysosomes will accumulate non-degradable products
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| − | *** E.g. lipofuscin - the 'ageing' or 'wear and tear pigment'.
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| − | **** Commonly seen in middle-aged cats in the hepatocytes nearest the centrilobular veins.
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| − | ===Intracellular Bacteria===
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| − | * For example, [[:Category:Mycobacterium species|''Mycobacterium tuberculosis'']] in macrophages.
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| − | ===Protein Accumulation===
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| − | * In the renal tubular epithelium.
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| − | * Occurs when there is leakage of protein out through a damaged glomerulus.
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| − | [[Category:Degenerations and Infiltrations]]
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