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− | ===Characteristics===
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− | *Formerly known as ''Actinomyces pyogenes'' and ''Corynebacterium pyogenes''
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− | *Small facultatively anaerobic rod
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− | *Grows slowly on blood agar to produce small, white colonies surrounded by a zone of beta-haemolysis after 48 hours
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− | *Produces hazy haemolysis after 24 hours; pin-point colonies after 48 hours
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− | *Coryneform morphology, like Chinese characters; may be curved with slightly swollen ends
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− | *Found in nasopharyngeal mucosa and genital tract of cattle, sheep, pigs
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− | ===Pathogenicity===
| + | #REDIRECT[[Arcanobacterium pyogenes]] |
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− | *Opportunistic infections following injury or viral/mycoplasma infection in ruminants and pigs
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− | *Extracellular toxins including haemolysin, proteases, DNase and neurominidase
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− | *Haemolytic toxin, pyolysin, member of the thiol-activated cytolysins (pore-forming toxins); possibly cytotoxic to phagocytic cells; dermonecrotising activity
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− | ===Clinical infections===
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− | *Suppurative infections
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− | *Abscesses especially in liver
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− | *Lymphadenitis, [[Bones - inflammatory#Osteomyelitis|osteomyelitis]], peritonitis and neural abscessation
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− | *Pyometra
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− | *Endometritis
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− | *Summer mastitis
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− | *Ovine foot disease
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− | *[[Joints - inflammatory#In Sheep|Arthritis]] of sheep post-dipping; [[Joints - inflammatory#In Pigs|arthritis in pigs]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]]
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− | *Umbilical infections
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− | *[[Bacterial infections#Acute exudative pneumonia|Acute exudative pneumonia]] and contributes to [[Bacterial infections#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]
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− | *May cause [[Muscles - inflammatory#Abscesses|myositis]]
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− | *Unclassified ''Actinomyces'' species isolated from closed cases of [[Bursae and Tendons - inflammatory#Poll Evil and Fistulous Withers|Poll Evil and Fistulous Withers]]
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− | ===Treatment===
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− | *Penicillin or broad spectrum antibiotics
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