|
|
| (3 intermediate revisions by 3 users not shown) |
| Line 1: |
Line 1: |
| − | {{toplink
| + | #REDIRECT[[:Category:Spleen - Pathology]] |
| − | |backcolour = f5fffa
| |
| − | |linkpage =Lymphoreticular & Haematopoietic System - Pathology
| |
| − | |linktext =Lymphoreticular & Haematopoietic System
| |
| − | |maplink = Lymphoreticular & Haematopoietic System (Content Map) - Pathology
| |
| − | |sublink1 =Secondary Lymphoid System - Pathology
| |
| − | |subtext1 =SECONDARY LYMPHOID SYSTEM
| |
| − | }}
| |
| − | <br>
| |
| − | ''NB:Be aware of age-related changes regarding the spleen''
| |
| − | ==Anatomy & Physiology==
| |
| − | [[Spleen - Anatomy & Physiology|See here]] | |
| − | ==Splenic Lesions==
| |
| − | *splenomegaly is the main clinical finding associated with the spleen in disease
| |
| − | ===Splenitis===
| |
| − | ===Anthrax===
| |
| − | ===Torsion===
| |
| − | ===Haemolytic Anaemia===
| |
| − | ===Chronic Venous Congestion===
| |
| − | *this may be seen along with chronic venous congestion of the liver in cases of chronic cardiac failure
| |
| − | ===Barbituates===
| |
| − | * administration of barbituates can produce a degree of splenomegaly due to splenic engorgement by erythrocytes
| |
| − | ===Splenic Tumours===
| |
| − | *these are important surgically since splenomegaly can be diagnoses clinically by palpation or X-ray and some are surgically curable
| |
| − | ====Hyperplastic Nodules or Benign Lymphoma====
| |
| − | *very common incidental findings in older dogs
| |
| − | *should not be mistakenly identified as pathognomic lesions
| |
| − | *consist of nodules of hyperplastic white and red pulp
| |
| − | :- usually 1-2 cms in size, but occasionally may be larger
| |
| − | :- spherical | |
| − | :- protrude hemispherically from the surface as yellow and red mottled nodules | |
| − | *infrequently, may rupture and give rise to haemorrhage
| |
| − | ====Haemangioma====
| |
| − | *benign tumour of dogs
| |
| − | *may grow to considerable size
| |
| − | :- the size of the lesion giving rise to clinical signs is compounded by haemorrhage from and into the tumour
| |
| − | :- thus, a large mass of apple size may be found protruding from the spleen and adherent to the omentum
| |
| − | *on section, it is largely blood clot
| |
| − | *responds well to surgery
| |
| − | :- therefore it must be distinguished from haemangiosarcoma
| |
| − | ====Haemangiosarcoma====
| |
| − | *highly malignant tumour of dogs
| |
| − | *distinguished from the superficially similar haemangioma by the presence of much more formed, solid tumour tissue
| |
| − | *accurate prognosis demands histological examination
| |
| − | *secondaries are common locally in the [[Peritoneal cavity - Anatomy & Physiology#Omentum|omentum]] and in the [[Liver - Anatomy & Physiology|liver]]
| |
| − | :- course is usually short, often only a month or two
| |
| − | :- metastases may occur in almost every organ
| |
| − | ====Haematopoietic Neoplasms====
| |
| − | =====lymphosarcoma=====
| |
| − | * splenomegaly occurs in multicentric lymphosarcoma
| |
| − | *splenic enlargement may be marked if any form of lymphosarcoma is in leukaemic phase
| |
| − | =====myeloid (granulocytic) leukaemia=====
| |
| − | *rare
| |
| − | *all species
| |
| − | *extreme form with spleen approaching liver size
| |
| − | =====systemic mastocytosis=====
| |
| − | *cat
| |
| − | *extreme form with spleen approaching liver size
| |
| − | ===Infarction===
| |
| − | ===Rupture===
| |