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| − | {{toplink
| + | #redirect[[Reproductive Hormones Overview - Anatomy & Physiology]] |
| − | |backcolour = FAFAD2
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| − | |linkpage =Endocrine System - Pathology
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| − | |linktext =Endocrine System
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| − | |maplink = Endocrine System (Content Map) - Pathology
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| − | |pagetype =Pathology
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| − | }}
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| − | <br>
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| − | Sex hormones are produced by the zona reticularis of the adrenal glands in addition to those produced by the ovary and testis:
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| − | *'''Testis''': Produces '''androgens''':
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| − | **Increase mitoses in skin.
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| − | **Increase sebaceous secrretion.
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| − | **Increase hair growth.
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| − | *'''Ovary''': Produces '''oestrogens''' and '''progesterone'''. Effects of oestrogens include:
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| − | **Decreased collagen production.
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| − | **Decreased sebaceous secretion.
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| − | **Decreased epidermal thickness.
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| − | **Decreased hair growth.
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| − | **Increased skin pigmentation.
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| − | ==Hyperoestrogenism==
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| − | ===Females===
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| − | '''''Ovarian Imbalance Type 1'''''
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| − | Seen in adult bitches who present with alopecia and increased pigmentation round the perianal, perigenital and axillary areas.
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| − | Caused by:
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| − | *Cystic ovaries.
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| − | *Ovarian neoplasia.
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| − | ===Males===
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| − | Dogs present with bilaterally symmetric alopecia, similar hyperpigmentation to that seen with female dogs with ovarian imbalance, loss of libido and gynaecomastia. The dogs become attractive to other male dogs.
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| − | Caused by:
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| − | *[[Sertoli cell tumour]].
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| − | *[[Male feminising syndrome]].
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| − | ==Hyperandrogenism==
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| − | ===Females===
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| − | '''''Ovarian Imbalance Type 2'''''
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| − | Seen in young bitches spayed early. Develop alopecia of perineum, ventral neck, chest and abdomen. Bitch will have immature nipples and vulva and may diplay incontinence.
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| − | ''Treatment'':
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| − | May respond to small doses of oestrogens.
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| − | ===Males===
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| − | *Perianal gland hyperplasia.
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| − | *Tail gland hyperplasia.
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| − | *Seborrhoea.
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