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− | {{unfinished}}
| + | #REDIRECT[[Equine Viral Arteritis]] |
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− | {{toplink
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− | |linkpage =Viruses
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− | |linktext =VIRUSES
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− | |sublink1=Arteriviridae
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− | |subtext1=ARTERIVIRIDAE
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− | |pagetype =Bugs
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− | }}
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− | <br>
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− | ====Antigenicity====
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− | *Most cases are subclinical and only '''antibody positive'''
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− | ====Hosts====
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− | *More common in '''thoroughbreds'''
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− | ====Pathogenesis====
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− | *Infects nasopharynx and spreads locally, causing:
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− | **Dypsnoea
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− | **Coughing
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− | **Diarrhoea
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− | **Colic
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− | *Spread to lymphoid tissue leads to '''leukopenia''' and '''immunosuppression'''
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− | *Typical '''medial necrosis of arteries''' causing:
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− | **Hemorrhage
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− | **Abortions occur after 10-30 days in 50% of pregnant mares (as opposed to Equine Herpes, which shows late abortions)
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− | **Oedema - particularly ocular, giving rise to "pink eye"
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− | *Other clinical signs include:
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− | **Pyrexia
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− | **Nettle rashes
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− | **Ocular and nasal discharge
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− | **Swelling of legs or scrotum
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− | **Stiffness of gait
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− | *'''Foal death''' caused by '''interstitial pneumonia'''
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− | *Stallions become intermittent or persistent '''shedders''' from [[Male Reproductive Tract -Accessory Sex Glands - Anatomy & Physiology|accessory sex glands]] but may show no clinical signs
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− | ====Epidemiology====
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− | *Controlled virus in the UK but AI and breeding schemes presents a real risk
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− | ====Diagnosis====
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− | *Clinical symptoms, but may be variable
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− | *'''PCR''' on '''semen'''
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− | *'''ELISA''' for serum '''antibody'''
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− | ====Control====
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− | *'''Vaccines''':
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− | **Stallions: '''Live attenuated'''
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− | **Mares: '''Killed whole virus'''
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− | *Clinical disease is '''NOTIFIABLE'''
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− | **Seropositive stallions restricted from teasing, mating or AI unless PCR tested negative
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− | **Persistent shedders should be castrated
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− | *Serology on imported horses
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− | *Mares tested within 4 weeks of mating
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− | *In an outbreak, isolate and restrict movement until antibody-negative for one month
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