Difference between revisions of "Skin Other - Pathology"

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#REDIRECT[[:Category:Integumentary System - Pathology]]
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==Epidermal growth or differentiation disorders==
 
 
 
===Seborrheic disease complex===
 
*Abnormal cornification or function of sebaceous glands
 
*Large amounts of free fatty acids and cholesterol
 
*Decreased amounts of diester waxes in surface lipids
 
*Bacterial population changes to pathogenic [[Staphylococcus spp.|coagulase positive staphylococci]]
 
*Chronic disease affecting mainly dogs, sometimes cats and horses
 
*Dry form - white to grey scales
 
*Greasy form - scaly, excess brown to yellow lipids sticking to skin and hair
 
 
 
===Primary idiopathic seborrhea===
 
*Abnormal cornification
 
*Epidermal turnover reduced to about 2/3 of normal
 
*Microscopically:  
 
**Hyperkeratosis distending follicular ostia causing papillary appearance
 
**Parakeratosis at edges of follicular ostia
 
**Congested, oedematous dermal papillae
 
**Spongiotic epidermis with leukocytes
 
 
 
===Secondary seborrhea===
 
*Develops secondarily to many types of disease (''e.g.'' [[Parasitic skin infections - Pathology|ectoparasites]], [[Mycotic skin infections - Pathology|fungal infections]], [[Endocrine effects on the skin - Pathology|endocrine disease]], internal disease or allergy)
 
*Microscopically:
 
**Hyperkeratosis and/or parakeratosis of follicles and epidermis
 
**Lesions relevant to the other disease
 
 
 
===Sebaceous adenitis===
 
*Inflammation of sebaceous glands, alopecia, hyperkeratosis
 
*Possibly immune-mediated
 
*Mainly affects dogs
 
**Long haired show multifocal, serpiginous and annular lesions
 
*Microscopically:
 
**Inflammation of sebaceous glands
 
**Possibly orthokeratotic hyperkeratosis
 
**Chronic lesions are deprived of sebaceous glands and contain mild inflammation and fibrosis at follicular isthmus
 
 
 
==Pigmentation disorders==
 
===Hypopigmentation===
 
===Hyperpigmentation===
 
==Eosinophilic infiltration==
 
===Eosinophilic plaques===
 
===Eosinophilic granulomas===
 
===Eosinophilic folliculitis and furunculosis===
 
==Sterile granulomatous disorders==
 
===Juvenile pyoderma===
 
===Equine generalised granulomatous disease===
 

Latest revision as of 18:33, 22 February 2011