Difference between revisions of "Shigella"

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*Not significant cause of infection in domestic animals
 
*Not significant cause of infection in domestic animals
*Causes [[Intestine Pathogens - Pathology#Dysentery in Humans and Primates|dysentery in humans and primates]]
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*Causes dysentery in humans and primates
 
*Enteroinvasive, invading the intestinal mucosa and causing necrosis
 
*Enteroinvasive, invading the intestinal mucosa and causing necrosis
 
*Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
 
*Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
 
*A large plasmid permits survival in cells and is responsible for invasivenss
 
*A large plasmid permits survival in cells and is responsible for invasivenss
 
*Closely related to [[Escherichia coli|''E. coli'']] - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli''
 
*Closely related to [[Escherichia coli|''E. coli'']] - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli''
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* Cause of dysentery in humans and primates.
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===Dysentery in Humans and Primates===
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* [[Shigella|''Shigella'']] is are enteroinvasive,
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** Penetrate the intestinal mucosa.
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** Cause necrosis in patches of mucosa.
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* [[Shigella|''Shigella'']] do not invade beyond the lamina propria to the bloodstream.
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* Invasive potential is carried by a large plasmid.
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** Relates to the ability to survive inside the host cells.
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* Some strains produce Shiga toxin.
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** Related to vero cytotoxin of some pathogenic strains of [[Escherichia coli|''E.coli'']].
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[[Category:Enterobacteriaceae]]
 
[[Category:Enterobacteriaceae]]
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[[Category:Enteritis,_Bacterial]]
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[[Category:To_Do_-_Bacteria]]

Latest revision as of 10:44, 25 June 2010

  • Not significant cause of infection in domestic animals
  • Causes dysentery in humans and primates
  • Enteroinvasive, invading the intestinal mucosa and causing necrosis
  • Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
  • A large plasmid permits survival in cells and is responsible for invasivenss
  • Closely related to E. coli - some strains produce Shiga toxin which is related to vero cytotoxin of E. coli
  • Cause of dysentery in humans and primates.

Dysentery in Humans and Primates

  • Shigella is are enteroinvasive,
    • Penetrate the intestinal mucosa.
    • Cause necrosis in patches of mucosa.
  • Shigella do not invade beyond the lamina propria to the bloodstream.
  • Invasive potential is carried by a large plasmid.
    • Relates to the ability to survive inside the host cells.
  • Some strains produce Shiga toxin.
    • Related to vero cytotoxin of some pathogenic strains of E.coli.