Difference between revisions of "Category:Retroviridae"

Latest revision as of 00:09, 16 June 2016

Retroviridae

Retroviruses are persistent, non-cytopathic, systemic viruses that give rise to secondary disease, such as tumors, immune-complex disease, or immunosuppression.

Content

▼ Retroviridae
► Lentiviruses
► Mammalian Type C retrovirus
► Mammalian Type D retrovirus
Avian Leukosis Virus
Bovine Leukaemia Virus
Retroviridae Overview
Spumavirus

Retroviridae Learning Resources

Vetstream
To reach the Vetstream content, please select Canis, Felis, Lapis or Equis

Subcategories

This category has the following 3 subcategories, out of 3 total.

L

► Lentiviruses‎ (5 P)

M

► Mammalian Type C retrovirus‎ (1 P)
► Mammalian Type D retrovirus‎ (1 P)

Pages in category "Retroviridae"

The following 4 pages are in this category, out of 4 total.

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+{{frontpage
+|pagetitle =Retroviridae
+|pagebody = Retroviruses are persistent, non-cytopathic, systemic viruses that give rise to secondary disease, such as tumors, immune-complex disease, or immunosuppression.
+|contenttitle =Content
+|contentbody =<big><b>
+<categorytree mode=pages>Retroviridae</categorytree>
-[[File:FeLV logo.jpg]]
+|logo =FeLV logo.jpg
+}}
+{{Learning |Vetstream = <p>[https://www.vetstream.com/felis/Content/Bug/bug60015.asp Feline Immunodeficiency Virus]</p><p>[https://www.vetstream.com/felis/Content/Bug/bug60014.asp Feline Leukemia Virus]</p>}}
-=Introduction=
-Retroviruses are persistent, non-cytopathic, systemic viruses that give rise to secondary disease, such as tumors, immune-complex disease, or immunosuppression.
-=Morphology=
-*Fragile, enveloped RNA viruses with roughly spherical spike proteins
-*Genome has 3 genes:
-**''gag'': group-specific antigen coding gene, encodes capsid proteins
-**''pol'': encodes reverse transcriptase (RT) and integrase
-**''env'': encodes envelope spikes, and can be used in diagnosis and subunit vaccines
-*Both ends of genome show a promoter (LTR: long terminal repeat)
-=Antigenicity=
+[[Category:Viral Organisms]]
-*Group-specific antigens (gag's) are shared by all isolates of each virus
+[[Category:To_Do_-_Clinical/Viruses]]
-**This can be exploited by diagnostic tests
-*Lentiviruses show variation by mutation, making vaccination difficult
-=Virulence and Pathogenesis=
-*Replication involves integrating into the host cell genome:
-**'''Uncoating''' to release RNA and RT
-**+RNA '''transcribed''' to -DNA by RT
-**-DNA becomes circular dsDNA and is '''integrated''' into host chromosome by integrase
-**DNA '''codes''' for viral proteins using cellular organelles and enzymes
-**Because of this technique, virus replication is much '''slower''', and retroviruses can remain '''latent'''
-*Tumor production takes 2 forms:
-**Viruses can carry oncogenes within their genome --> tumor production occurs quickly
-**Insertion of the viral LTR switches on proto-oncogenes in the host cell genome --> tumor production can take years
-=Types and Subtypes=
-Genera, including these of veterinary relevance:
-#[[Mammalian Type C retrovirus]]
-#[[Mammalian Type D retrovirus]]
-#
-#[[Avian Type C retrovirus]]
-#
-#[[Spumavirus]]
-#BLV-HTLV retroviruses
-#*Bovine Leukosis Virus
-#Lentiviruses
-#*[[Feline Immunodeficiency Virus (FIV)]]
-#*Bovine Immunodeficiency Virus
-#*[[Visna-Maedi Virus of Sheep]]
-#*[[Caprine Arthrirtis Encephalitis Virus]]
-#*[[Equine Infectious Anemia]]
-#*Jembrana of Bali cattle
-#*Human Immunodeficiency Virus (HIV)
-[[Category:Viruses]]