Difference between revisions of "Arterial Diseases - WikiClinical"

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#REDIRECT[[:Category:Cardiovascular Diseases - Dog]]
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==[[Hypertension, Systemic]]==
 
 
 
 
 
===[[Pulmonary Hypertension]]===
 
 
 
 
 
 
 
==[[Thrombosis]]==
 
 
 
==Thromboembolism==
 
[[Image:sarcoma embolus.jpg|right|thumb|125px|<small><center>'''Sarcoma embolus (dog)'''. Courtesy of T. Scase</center></small>]]
 
 
 
===Description===
 
 
 
*As the name implies, a thromboembolism is a clot (thrombus) or foreign body that blocks vessels a distance away from its original site of origin. 
 
 
 
*The most significant sites of thromboembolic formation are the following: lungs, CNS, terminal aorta, kidneys.
 
 
 
 
 
'''Requirements for thromboembolism formation:
 
'''
 
 
 
1. Disruption of endothelial integrity
 
 
 
2. Disruption of flow
 
 
 
3. Disruption of blood haemostasis
 
 
 
4. Disruption of fibrinolysis
 
 
 
 
 
'''The incidence of thromboembolism greatly increases with certain diseases including:
 
'''
 
 
 
-Heart Disease
 
 
 
-Neoplasia
 
 
 
-Blood Disorders
 
 
 
-Parasitic Diseases
 
 
 
-Hyperadrenocorticism
 
 
 
 
 
====Diagnosis====
 
 
 
=====History & Clinical Signs=====
 
 
 
'''5 P's:'''
 
 
 
-Pain
 
 
 
-Paresis
 
 
 
-Pallor
 
 
 
-Pulselessness
 
 
 
-Polar (cold extremities)
 
 
 
 
 
'''Long Term Effects:'''
 
 
 
-Necrosis
 
 
 
 
 
'''Specific Problems:'''
 
 
 
*Signs are dependant on site of thromboembolism
 
 
 
-Neurological problems (acute)
 
 
 
-Renal Failure (acute)
 
 
 
-Dyspnoea (acute)
 
 
 
 
 
====Laboratory Findings====
 
 
 
*Heavily dependent on thromboembolic site
 
 
 
 
 
-Hyperkalemia
 
 
 
-Acidosis
 
 
 
-Increased Lactate
 
 
 
-Azotemia
 
 
 
-Elevated serum creatine phospohokinase
 
 
 
 
 
====Radiography, Echocardiography, Angiography====
 
 
 
-Clots may be seen by the above methods
 
 
 
===Treatment===
 
 
 
-Treat underlying conditions
 
 
 
-Pain Relief (e.g. morphine)
 
 
 
-Support with IV fluids
 
 
 
-Anticoagulants:
 
 
 
1. Heparin
 
 
 
2. Aspirin
 
 
 
 
 
===Prognosis===
 
 
 
-Grave
 
 
 
==Arteriovenous Fistula==
 
 
 
===Description===
 
 
 
*As the name implies, an arteriovenous fistula is an abnormal direct connection between an artery and a vein.  This connection causes the capillary circulation to be completely ignored.  We will concentrate on peripheral fistulas here. 
 
 
 
 
 
'''The consequences of an arteriovenous fistula are the following:'''
 
 
 
1. Increased blood return to the right heart raises cardiac output
 
 
 
2. Decreased blood perfusion at the affected site
 
 
 
3. Venous hypertension
 
 
 
 
 
*Predisposing causes of arteriovenous fistula formations are: trauma, surgery, neoplasia, etc.
 
 
 
 
 
===Diagnosis===
 
 
 
====History & Clinical Signs====
 
 
 
*Signs depend on where the AV fistula has formed.
 
 
 
-Subcutaneous edema
 
 
 
-Warm Swelling
 
 
 
-Inflammation
 
 
 
-Pain +/-
 
 
 
-Palpable vibration (thrill) over fistula
 
 
 
-Increased pulse & heart rate
 
 
 
-Audible continuous murmur over the fistula site
 
 
 
-Branham sign (decreased heart rate with surgical occlusion of blood flow to fistula)
 
 
 
 
 
====Angiography====
 
 
 
-Abnormal direct connection between an artery and a vein
 
 
 
 
====Ultrasonography====
 
 
 
-Abnormal flow visualized
 
 
 
 
 
===Treatment===
 
 
 
-Surgical ligation of abnormal vessels to and from the fistula area
 
 
 
-(+/-) Amputation
 
 
 
 
 
===Prognosis===
 
 
 
-Good with complete ligation and cessation of blood flow through the fistula
 
 
 
-Poor if surgical ligation is unsuccessful at stopping blood flow through the fistula
 
 
 
 
 
==Vasculitis==
 
 
 
===Description===
 
 
 
*Vasculitis is an inflammatory disease of the vessels. 
 
 
 
*Causes of vessel inflammation are due to the following: neoplasia, infection, toxins, drug reactions, trauma, drug reactions, hypersensativity reactions etc.
 
 
 
 
 
===Diagnosis===
 
 
 
====History & Clinical Signs====
 
 
 
-Heat
 
 
 
-Edema
 
 
 
-Pain
 
 
 
-Petechiation
 
 
 
-Thrombosis
 
 
 
-Hemolysis
 

Latest revision as of 15:38, 16 December 2010