Difference between revisions of "Category:Primary Immunodeficiency"

 
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*Primary immunodeficiencies may affect either the [[Innate Immune System - WikiBlood|innate immune system]] or the [[Adaptive Immune System - WikiBlood|adaptive immune system]]
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{{frontpage
*They are categorised by either the type or the developmental stage of the cells involved
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|pagetitle =Primary Immunodeficiency
*Lymphoid cell disorders affect [[Lymphocytes#T cells|T cells]] or [[Lymphocytes#B cells|B cells]] (or both)
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|pagebody =Primary immunodeficiencies may affect either the [[Innate Immune System|innate immune system]] or the [[Adaptive Immune System|adaptive immune system]]. They are categorised by either the type or the developmental stage of the cells involved. Lymphoid cell disorders affect [[Lymphocytes#T cells|T cells]] or [[Lymphocytes#B cells|B cells]] (or both). Myeloid cell disorders affect phagocytic function. The severity of the immunodeficiency depends on at which stage in development the problem occurs. E.g. Defects early on in development will affect the entire immune system.
*Myeloid cell disorders affect phagocytic function
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[[Lymphocytes#T cells|T cell]] deficiencies can affect both the cell-mediated and humoral response as [[Lymphocytes#T cells|T cells]] play a central role in the immune system.
*The severity of the immunodeficiency depends on at which stage in development the problem occurs
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|contenttitle = Content
**E.g. Defects early on in development will affect the entire immune system
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|contentbody =<big><b>
*[[Lymphocytes#T cells|T cell]] deficiencies can affect both the cell-mediated and humoral response as [[Lymphocytes#T cells|T cells]] play a central role in the immune system
 
  
[[Primary Innate Immunity Deficiencies]]
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<categorytree mode=pages>Primary Immunodeficiency</categorytree>
[[Primary Adaptive Immunity Deficiencies]]
 
  
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|logo = Immature MDDC.png
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}}
  
===Laboratory Examples of Severe Combined Deficiency===
 
[[Image:Nude Mouse.jpg|right|thumb|150px|Athymic Nude Mouse - Armin Kübelbeck 2008]]
 
*Severe Combined Immune Deficiency(SCID)
 
**No functional [[Lymphocytes#B cells|B cells]] or [[Lymphocytes#T cells|T cells]]
 
 
*Athymic nude mice (no [[Thymus - Anatomy & Physiology|thymus]])
 
**No functional [[Lymphocytes#T cells|T cells]]
 
**Cell-mediated immunodeficiency
 
 
*Knock-out mice
 
**E.g. Gene coding for  CD4, CD8, IL-10 removed
 
  
 
[[Category:Immunodeficiencies]]
 
[[Category:Immunodeficiencies]]

Latest revision as of 16:18, 13 August 2010

Primary Immunodeficiency

Primary immunodeficiencies may affect either the innate immune system or the adaptive immune system. They are categorised by either the type or the developmental stage of the cells involved. Lymphoid cell disorders affect T cells or B cells (or both). Myeloid cell disorders affect phagocytic function. The severity of the immunodeficiency depends on at which stage in development the problem occurs. E.g. Defects early on in development will affect the entire immune system. T cell deficiencies can affect both the cell-mediated and humoral response as T cells play a central role in the immune system.

Subcategories

This category has the following 2 subcategories, out of 2 total.

Pages in category "Primary Immunodeficiency"

This category contains only the following page.