Changes

A highly contagious acute respiratory disease spread by close contact causing laryngitis, tracheitis, bronchitis and in some cases a rhinitis.

A highly contagious acute respiratory disease spread by close contact causing laryngitis, tracheitis, bronchitis and in some cases a rhinitis.

Multiple agents are implicated in the disease including [[Canine Adenovirus 1|Canine Adenovirus 1]],[[Canine Adenovirus 2|Canine Adenovirus 2]],[[Canine Herpesvirus 1|Canine Herpes virus]], [[Canine Parainfluenza - 2|Canine Parainfluenza - 2]], [[Canine Distemper Virus|Canine Distemper Virus]], [[:Category:Mycoplasmas|Mycoplasma species]] and [[Bordetella bronchiseptica|''Bordetella bronchoseptica'']]. Most cases involve a primary viral infection and sometimes with secondary bacterial involvement. ''B.bronchoseptica'' adheres to ciliated epithelial cells in the trachea where it proliferates and releases toxins causing epithelial necrosis and prevents[[Diseases of the nasal cavity and sinuses#Mucociliary escalator| ciliary clearance]].  Mortality rates are very low and it is a common disease in dogs that are housed in groups.

Multiple agents are implicated in the disease including [[Canine Adenovirus 1|Canine Adenovirus 1]], [[Canine Adenovirus 2|Canine Adenovirus 2]], [[Canine Herpesvirus 1|Canine Herpes virus]], [[Canine Parainfluenza - 2|Canine Parainfluenza - 2]], [[Canine Distemper Virus|Canine Distemper Virus]], [[:Category:Mycoplasmas|Mycoplasma species]] and [[Bordetella bronchiseptica|''Bordetella bronchoseptica'']]. Most cases involve a primary viral infection and sometimes with secondary bacterial involvement. ''B.bronchoseptica'' adheres to ciliated epithelial cells in the trachea where it proliferates and releases toxins causing epithelial necrosis and prevents[[Diseases of the nasal cavity and sinuses#Mucociliary escalator| ciliary clearance]].  Mortality rates are very low and it is a common disease in dogs that are housed in groups.

==Signalment==

==Signalment==