Changes

[[Image:Panosteitis.jpg|right|thumb|100px|<small><center>Panosteitis (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

[[Image:Panosteitis.jpg|right|thumb|200px|<small><center>Panosteitis (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

Panosteitis is a '''spontaneous, self-limiting inflammatory disease''' of '''young, rapidly growing large or giant dogs'''. 75% of cases are seen in '''German Shepherd Dogs''' between 5 and 12 months of age. It is much more common in '''males''' than in females.

Panosteitis is a '''spontaneous, self-limiting inflammatory disease''' of '''young, rapidly growing large or giant dogs'''. 75% of cases are seen in '''German Shepherd Dogs''' between 5 and 12 months of age. It is much more common in '''males''' than in females.

:'''In the late phase''', the appearance of the medullary canal '''returns to normal'''. The thickened cortices and accentuated trabecular pattern are the last to resolve.

:'''In the late phase''', the appearance of the medullary canal '''returns to normal'''. The thickened cortices and accentuated trabecular pattern are the last to resolve.

Such lesions may be present in a single bone or in several bones.

Such lesions may be present in a single bone or in several bones. '''Repeat radiographs''' are helpful to assess the progression of the condition through the phases. Sometimes a definitive radiological diagnosis is never achieved because the clinical signs disappear before further radiographs are taken.

 

'''Repeat radiographs''' are helpful to assess the progression of the condition through the phases.

 

Sometimes a definitive radiological diagnosis is never achieved because the clinical signs disappear before further radiographs are taken.

'''Differential diagnoses''' would include: osteomyelitis and hypertrophic osteodystrophy.

'''Differential diagnoses''' would include: [[osteomyelitis]] and [[Hypertrophic Osteodystrophy|hypertrophic osteodystrophy]].

==Treatment==

==Treatment==

Panosteitis is treated '''conservatively''' using '''NSAIDs during episodes of lameness and pain''', with strict exercise restriction.

Panosteitis is treated '''conservatively''' using '''[[NSAIDs[[ during episodes of lameness and pain''', with strict exercise restriction.

'''Recurrent episodes''' can be expected and several courses of analgesia may be necessary. The disease is usually self-limiting in one to several months.

'''Recurrent episodes''' can be expected and several courses of analgesia may be necessary. The disease is usually self-limiting in one to several months.

Owners may be taught to recognise signs of early pain and can '''administer short courses''' of NSAIDs on an 'as needed' basis.  

Owners may be taught to recognise signs of early pain and can '''administer short courses''' of NSAIDs on an 'as needed' basis.  

The '''prognosis is excellen'''t and the disease is rarely seen past the age of 20 months.

The '''prognosis is excellent''' and the disease is rarely seen past the age of 20 months.

'''Excessive dietary supplementation''' in young, large-breed growing dogs should be avoided.

'''Excessive dietary supplementation''' in young, large-breed growing dogs should be avoided.

 

[[Category:To Do - Helen]]

[[Category:Musculoskeletal Diseases - Dog]]

[[Category:To Do - Review]]

[[Category:Expert Review - Small Animal]]

 

[[Category:Bones - Inflammatory Pathology]]

[[Category:Bones - Inflammatory Pathology]]