Inherited defects in the transporter for dibasic amino acids can result in poor absorption of lysine (as well as the other dibasic amino acids cystine, ornithine, and [[Arginine - Nutrition|arginine]]) from the intestinal mucosa and poor reabsorption of plasma lysine in the [[Nephron Microscopic Anatomy#Proximal Tubule|renal tubule]]<ref>Hoppe A, et al. Urinary excretion of amino acids in normal and cystinuric dogs. Br Vet J 1993;149:253-68.</ref>. | Inherited defects in the transporter for dibasic amino acids can result in poor absorption of lysine (as well as the other dibasic amino acids cystine, ornithine, and [[Arginine - Nutrition|arginine]]) from the intestinal mucosa and poor reabsorption of plasma lysine in the [[Nephron Microscopic Anatomy#Proximal Tubule|renal tubule]]<ref>Hoppe A, et al. Urinary excretion of amino acids in normal and cystinuric dogs. Br Vet J 1993;149:253-68.</ref>. |