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*Most mice show no symptoms due to maternal antibodies
*Most mice show no symptoms due to maternal antibodies
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
*Immunological studies also confused due to virus activating [[General Pathology - Antigen Recognition, Processing and Presentation#NK Receptors|NK cells]] via high circulating [[General Pathology - Innate Immunity#Interferons|IF]] 3-4 days post-infection
*Immunological studies also confused due to virus activating [[General Pathology - Antigen Recognition, Processing and Presentation#NK Receptors|NK cells]] via high circulating [[Innate Immunity - Anatomy & Physiology#Interferons|IF]] 3-4 days post-infection
*Control achieved by:
*Control achieved by:
**Purchasing specific pathogen free (SPF) mice
**Purchasing specific pathogen free (SPF) mice