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*Most mice show no symptoms due to maternal antibodies
 
*Most mice show no symptoms due to maternal antibodies
 
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
 
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
*Immunological studies also confused due to virus activating [[General Pathology - Antigen Recognition, Processing and Presentation#NK Receptors|NK cells]] via high circulating [[Innate Immunity - Anatomy & Physiology#Interferons|IF]] 3-4 days post-infection
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*Immunological studies also confused due to virus activating [[General Pathology - Antigen Recognition, Processing and Presentation#NK Receptors|NK cells]] via high circulating [[Innate Immune System - WikiBlood#Interferons|IF]] 3-4 days post-infection
 
*Control achieved by:
 
*Control achieved by:
 
**Purchasing specific pathogen free (SPF) mice
 
**Purchasing specific pathogen free (SPF) mice

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