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===Presentation Pathway===
 
===Presentation Pathway===
 
*Viral proteins are broken down to peptides by the proteasome and transferred to the endoplasmic reticulum via TAP (Transporters associated with Antigen Processing) molecules
 
*Viral proteins are broken down to peptides by the proteasome and transferred to the endoplasmic reticulum via TAP (Transporters associated with Antigen Processing) molecules
*In the ER< peptides are processed with empty MHC I molecules and exported to the cell surface for presentation
+
*In the ER peptides are processed with empty MHC I molecules and exported to the cell surface for presentation
* MHC class I molecules bind antigenic peptides derived from within the cell and present these to the T-cell receptors of '''CD8+ T-cells'''
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* MHC class I molecules present these to the T-cell receptors of [[Lymphocytes - WikiBlood#Cytotoxic CD8+|'''CD8+ T-cells''']]
* Endogenously produced proteins are produced in the cell cytoplasm
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** Intracellular pathogens utilise this cellular metabolic machinery for protein synthesis
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** Many of the proteins synthesised are not used and are re-utilised by the cell
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*** Peptides from these proteins are transported to the Golgi apparatus by specific transporter molecules
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*** These peptides then interact with newly synthesized MHC class I molecules.
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* Only MHC class I that is associated with peptide will be expressed at the surface
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** The immune system is therefore able to see antigen from intracleeular pathogens
      
==MHC II==
 
==MHC II==
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