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==Sporotrichosis==
==Sporotrichosis==
*''Sporothrix schenckii''
*Occurs in soil, wood and vegetation
*Worldwide
*Exogenous infections through wounds
*Causes subcutaneous nodules or granulomas
**Nodules ulcerate discharging pus
*Spread via the lymphatics
*The bones and viscera can be involved which terminates in mortality
**This is rare
**Reported in dogs and horses
*Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents
**Most commonly seen in horses as an ascending lymphocutaneous infection of the legs
*Single cell, cigar shaped
**Usually found within neutrophils
**Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections
*Stained using PAS, fluorescent antibody and Calcofluor White
*Latex agglutination and immunodiffusion serology can be performed
*Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks
*At 37°C:
**Colonies are smooth, cream to tan coloured and soft
**No mycelium can be seen
*At 25°C to 27°C:
**Colonies turn from white and soft to tan to brown to black
**Leathery, wrinkled and coarse
**Mycelium can be seen as branching septate hyphae
**Conidiospores can also be seen
*Potassium iodide treatment orally
**[[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]] can also be used
==Further Links==
==Further Links==